Spontaneous Acoustic Tumor Involution: A Case Report

Spontaneous Regression of a Growing Vestibular Schwannoma-Case Report-

“…2) Except for these patients, no similar case was described in the literature on spontaneous regression. 6,7,[10][11][12][14][15][16][17][18] The clinical features in patients managed conservatively were investigated to identify the tumor growth-promoting factors. Although no predisposing factor to predict tumor growth was identified, 12,14,16) patient age was correlated with tumor growth.…”

“…This phenomenon has not been described in cases of spontaneous regression. 2,4,6,[10][11][12] Prospective studies to identify the prognostic factors underlying spontaneous regression are needed for better conservative management of vestibular schwannoma.…”

Clinical Growth Rate of Acoustic Schwannomas: Correlation with the Growth Fraction as Defined by the Monoclonal Antibody Ki-67

“…The results of articles dealing with the radiologic assessments of growth rates are summarized in Table 4. These studies do not all use the same methods of There appear to be three different and to a great extent separate tumor growth rates: (1) Those that do not grow, regress, or grow at a rate of 0.02 cm/year, taking 50 years to reach 1 cm; (2) those that grow at 0.2 cm/year; and (3) those that grow at around 1.0 cm/year. There may be a fourth growth rate, since some of the larger tumors appear to grow at a rate equivalent to 2.5 cm/yr.…”

Malignant Vestibular Schwannoma

“…Some authors have advocated conservative nonsurgical management of acoustic neuromas, especially in older patients.9 10 Slow growth ratesl2-14 as well as occasional spontaneous tumor "involution" 15,16 Pl .…”