Spontaneous Arterial Calcification: A Possible Etiology for Spontaneous Splenic Rupture in a Patient on Maintenance Hemodialysis

Abstract

Spontaneous splenic rupture (SSR) is a rare condition in contrast to traumatic splenic hematoma, and vascular abnormality has rarely mentioned as an etiology in SSR with patients who had chronic kidney disease. We reported a 80-year-old female whose SSR might be related to splenic arterial calcification. i 2014 S. Karger AG, Basel

Spontaneous Splenic Rupture following Colorectal Surgery and Hemodialysis

“…There are many risk factors including the use of heparin, amyloidosis, the immune-compromised status of patients that makes them susceptible to infections, and uremic coagulopathy [3, 7]. The latter is thought to be the main cause of spontaneous splenic rupture in hemodialyzed patients [3, 9].…”

“…Patients on dialysis are likely to have an abnormal coagulation profile. This may be evident in the form of prolonged bleeding time, platelet dysfunction, impaired platelet aggregation, decreased activity of platelet factor III, and impaired prothrombin consumption [7, 9]. Patients may show a fibrinolysis defect at the level of the plasminogen that may contribute to the development of atherosclerosis and thrombosis and subsequent complications.…”