Spontaneous Bacterial Peritonitis (Sbp); Assessment of Spontaneous Bacterial Peritonitis (Sbp) in Patients of Hepatic Encephalopathy and Its Association With Grades of He

Abstract

ABSTRACT… Objectives: To assess the SBP in patients with Hepatic Encephalopathy and its association with grades of hepatic encephalopathy. Study Design: Cross sectional study. Setting: Department of Medicine, Medina Teaching Hospital. Period: January 2017 to June 2017. Material and Methods: Total 143 patients of HE having age range from 18-65 years either male or female selected. SBP was assessed in these selected patients. SBP defined as positive when ascetic fluid neutrophil count > 250/ml. West heaven criteria was used for grading of HE. Results: In present study, mean age of patients was 37.45 ± 10.63 years. Out of 143 patients, SBP was found in 77 (54%) patients. HBsAg was found positive in 58 (40.56%) patients followed by Anti-HCV was found positive in 77 (53.85%) patients and Both Anti-HCV & HBsAg was found positive in 8 (5.59%) patients. Total 51 (35.66%) patients were found with grade I HE followed by 60 (41.96%) patients grade II, 23 (16.08%) patients grade III and 9 (6.29%) patients found with grade IV HE. SBP was found in 36 (70.59%) patients, 32 (53.33%) patients, 5 (21.74%) patients and 4 (44.44%) patients respectively. Statistically significant association between grade of HE and SBP was noted with p value 0.001. Conclusion: Results of present revels that frequency of SBP is very high in cases of HE. Hepatitis C was found positive in most of the patients. Statistically insignificant association of SBP with gender was observed. But highly significant association of SBP with grade of HE was seen. Key words:Hepatic encephalopathy, Cirrhosis, Spontaneous bacterial peritonitis, Ascites Article Citation: Ghafoor A, Ahmed I, Javid RA. Spontaneous bacterial peritonitis (SBP); Assessment of spontaneous bacterial peritonitis (SBP) in patients of hepatic encephalopathy and its association with grades of HE.