Spontaneous clearance of hepatitis C virus after long‐term opiate dependence therapy with buprenorphine

A 5‐year prospective study of the late resolution of chronic hepatitis C after antiviral therapy

“…the ability of a virus to replicate under the selective forces present in its environment 16 ) or an enhancement of anti-HCV host defences has been hypothesized to precede viral clearance: presence of very large liver cancers able to reduce the number of infected cells, 8 immune response restoration, 12,13 HBV superinfection, 9 use of immunomodulant drugs 10,11 and pregnancy.…”