Spontaneous corneal perforation in ocular rosacea

Arfaj, Khalid Al; Zamil, Waseem Al

doi:10.4103/0974-9233.63070

Cited by 32 publications

(14 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It was found to decrease the concentration of MMP-8 and MMP-9 in the tear film [17, 20]. Topical antibiotics have been used to alter the flora of the ocular surface in addition to topical steroids [34, 37]. …”

Section: Discussionmentioning

confidence: 99%

Ocular Rosacea Causing Corneal Melt in an African American Patient and a Hispanic Patient

Saade

Abiad

Jan

et al. 2017

Case Reports in Ophthalmological Medicine

View full text Add to dashboard Cite

Purpose To discuss two rare presentations of ocular rosacea in a Hispanic patient and an African American patient with unusual ocular manifestations. Case Report Case 1: a 43-year-old Hispanic woman presented with right eye corneal perforation. Her prior medical history was significant for rosacea only, diagnosed clinically by a dermatologist. Her eye exam showed signs of bilateral ocular rosacea. An emergent full thickness tectonic corneal patch graft was done. The patient's bilateral eye symptoms improved one month after initiating rosacea treatment. Case 2: a 51-year-old African American man with long standing history of untreated rosacea presented with bilateral peripheral corneal thinning with neovascularization that led to right eye corneal perforation. Glue and bandage contact lens were applied. The patient did well 4 weeks after starting antibacterial, oral steroids, and rosacea treatment. Discussion Ocular rosacea can present in Hispanic and African American patients with severe manifestations such as corneal perforation.

show abstract

Section: Discussionmentioning

confidence: 99%

Ocular Rosacea Causing Corneal Melt in an African American Patient and a Hispanic Patient

Saade

Abiad

Jan

et al. 2017

Case Reports in Ophthalmological Medicine

View full text Add to dashboard Cite

show abstract

“…The most severe sight-threatening complications of ocular rosacea are stromal thinning and corneal perforation. 27 , 28 , 29 The underlying cause of corneal thinning has not been clearly determined, but an elevated level of matrix metalloproteinases (especially type 9) in the inferior tear meniscus is believed to be responsible for stromal thinning and perforation. 5 There is very little information in the literature about corneal perforation in patients with ocular rosacea.…”

Section: Discussionmentioning

confidence: 99%

Clinical Findings, Follow-up and Treatment Results in Patients with Ocular Rosacea

Müftüoğlu¹,

Akova²

2016

tjo

View full text Add to dashboard Cite

Objectives:To report the clinical features, treatment options and complications in patients with ocular rosacea.Materials and Methods:The records of 48 eyes of 24 patients with ocular rosacea were retrospectively reviewed. Patients’ ocular signs and symptoms were scored between 1 and 4 points according to disease severity; tear film break-up time (BUT) and Schirmer’s test results were recorded before and after the treatment. Preservative-free artificial tears, topical antibiotic eye drops/ointments, short-term topical corticosteroids, topical 0.05% cyclosporine and oral doxycycline treatment were applied as a standard therapy to all patients. Additional treatments were given as needed. Complications were recorded.Results:Twenty-four patients with a mean age of 48.5±35.4 (32-54) years were followed for a mean 15±9.4 (8-36) months. Ocular findings included meibomitis in 100% of cases, anterior blepharitis in 83% (40 eyes), punctate keratopathy in 67% (32 eyes), chalazia in 50% (24 eyes), corneal neovascularization in 50% (24 eyes) and subepithelial infiltrates in 16.6% (8 eyes). Significant improvement of symptoms and clinical findings were achieved in all patients with treatment. The increases in Schirmer’s test and BUT were 3.3±1.5 and 4.5±2.8, respectively (p<0.05). Descemetocele and small corneal perforation occurred in 2 eyes; re-epithelialization was achieved in both eyes with tissue adhesive application (1 eye) and additional amniotic membrane transplantation (1 eye). Four eyes of three patients showed significant regression of corneal neovascularization with topical bevacizumab therapy.Conclusion:Ocular rosacea may present with a variety of ophthalmic signs. It is possible to control the ophthalmic disease with appropriate therapeutic modalities including topical corticosteroids, topical cyclosporine and systemic doxycycline.

show abstract

“…En la tabla 4, las regiones interpalpebrales e inferiores de la córnea son más susceptibles a daños, específicamente en posición horaria 3 y 9, debido al parpadeo y a la posición del menisco lagrimal inferior en reposo. En casos avanzados puede provocar un adelgazamiento corneal y pérdida del tejido estromal, lo cual precipita la formación de descementocele con riesgo de perforación corneal (34,35).…”

Section: Rosácea Ocularunclassified

Rosácea ocular: diagnóstico y manejo optométrico

Murcía¹,

Tobar²,

Alayón³

2019

Cienc. Tecnol. Salud Vis. Ocul.

View full text Add to dashboard Cite

RESUMENObjetivo: describir la rosácea ocular, con el fin de guiar un acertado diagnóstico y tratamiento. Materiales y métodos: se realizó una búsqueda sistemática de artículos de revisión disponibles en texto completo, en bases de datos como PubMed, Ebsco Host, Proquest, Medline, Elsevier, Scielo y Springer, así como textos literarios relacionados con el tema, escritos en inglés, español, alemán, francés y portugués. Se implementó una estrategia de búsqueda con palabras como "rosácea ocular", "manejo y fisiopatología de la rosácea", "ojo seco", "disfunción de glándulas de meibomio" y "Demodex". Se seleccionaron escritos con un periodo de publicación comprendido entre el 2000 y el 2015. Conclusión: el manejo de la enfermedad está direccionado al control de signos y síntomas mediante la aplicación de medidas conservadoras, terapia sistémica, aplicación tópica ocular, y en casos avanzados se opta por la intervención quirúrgica. Todo lo anterior permite afirmar que el objetivo principal de los profesionales de la salud visual es minimizar el daño ocular mediante la prevención de complicaciones futuras.Palabras clave: rosácea, rosácea ocular, manejo de ojo seco, fisiopatología de la rosácea, blefaritis, meibomitis, queratoconjuntivitis, Demodex.

show abstract

Spontaneous corneal perforation in ocular rosacea

Cited by 32 publications

References 8 publications

Ocular Rosacea Causing Corneal Melt in an African American Patient and a Hispanic Patient

Ocular Rosacea Causing Corneal Melt in an African American Patient and a Hispanic Patient

Clinical Findings, Follow-up and Treatment Results in Patients with Ocular Rosacea

Rosácea ocular: diagnóstico y manejo optométrico

Contact Info

Product

Resources

About