Spontaneous coronary artery dissection as the first presentation of systemic lupus erythematosus

Reddy, S. V.; Vaid, Tejasvini; Sanjeeva, Naveen Chandra Ganiga; Shetty, Ranjan

doi:10.1136/bcr-2016-216344

Cited by 22 publications

(24 citation statements)

References 15 publications

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“…Laboratory evaluation for inflammatory or autoimmune conditions is generally low yield but may be considered in the post-MI setting, particularly in patients who have symptoms of or physical examination findings of autoimmune or rheumatologic disease. SCAD has been described in case reports of patients with various systemic inflammatory diseases, including systemic lupus erythematosus, 97–102 inflammatory bowel disease, 103 polyarteritis nodosa, 104 sarcoidosis, 52 celiac disease, 105 and cryoglobulinemia in the setting of hepatitis C. 106 In these series, underlying coronary vasculitis 100 or systemic inflammation 100 may have contributed to the risk of SCAD, and larger cohort studies have shown that at least a small proportion of patients have either underlying inflammatory diseases or short-term increases in inflammatory markers. 13,60 Taken together, these series indicate that underlying inflammatory conditions may be predisposing factors in the development of SCAD in a small proportion of patients.…”

Section: Pathogenesis Of Scad and Scad-associated Conditionsmentioning

confidence: 99%

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Hayes¹,

Kim²,

Saw³

et al. 2018

Circulation

942

1,344

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Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented.

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Section: Pathogenesis Of Scad and Scad-associated Conditionsmentioning

confidence: 99%

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Hayes¹,

Kim²,

Saw³

et al. 2018

Circulation

942

1,344

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“…Six case reports have described SCAD in association with SLE. A recent case report attributed SCAD as a first presentation of SLE, however without clinical criteria for SLE and positive ANA and anti-SMA [19]. Systematic review has identified 40 previous cases published of SLE with aortic aneurysm and or dissection [20].…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Coronary Artery Dissection in a Patient with a Family History of Fatal Ascending Aortic Dissection: Case Report and Discussion of Diseases Causing Both Presentations

Joy

Eissa

2019

Case Reports in Cardiology

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Background Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS). Aortic dissection and SCAD share common aetiologies such as a fibromuscular dysplasia (FMD), Marfan, Ehlers Danlos, and more rarely systemic lupus erythematosus and Loeys-Dietz; however, SCAD has never been known to have a familial association with aortic dissection. Case Summary This case report describes a 48-year-old woman suffering from SCAD who had a mother who died from ascending aortic dissection in her 50s. Discussion This is the first case report to our knowledge of a patient with SCAD with a first-degree relative with aortic dissection. Our case is interesting in that it shows that if predisposition to arterial dissection was inherited from mother to daughter, one of them suffered an extremely rare manifestation of their underlying disease. It also shows that a high index of suspicion is needed for SCAD in the presence of a patient with ACS and a family history of dissection elsewhere in the arterial tree.

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“…However, six articles did not contain sufficient data and were excluded. After final exclusions, 10 articles were identified for data analysis [4][5][6][7][8][9][10][11][12][13]. Figure 1 presents a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart of the study selection process, along with reasons for study exclusion.…”

Section: Figure 1: Preferred Reporting Items For Systematic Reviews Amentioning

confidence: 99%

Spontaneous Coronary Artery Dissection Secondary to Rheumatological Diseases: A Comprehensive Review

Ullah¹,

Ali²,

Khanal³

et al. 2019

Cureus

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Spontaneous coronary artery dissection (SCAD) is a life-threatening condition and multiple conditions have been associated with this entity. This study aims to further investigate and characterize the association of the underlying rheumatological disease with SCAD. A comprehensive literature search on four databases was performed using different Medical Subject Headings (MeSH) and all articles on SCAD in association with rheumatological diseases were identified. The analysis was performed using the Statistical Package for Social Sciences (SPSS), v22 (IBM SPSS Statistics, Armonk, NY). Ten articles of SCAD secondary to rheumatological reasons were identified. The majority of presentations were associated with systemic lupus erythematosus (SLE). Most patients presented with a non-ST-elevation myocardial infarction (NSTEMI) involving the left main coronary vessel. The majority of them were successfully managed with stenting. Mortality was less than 20% with prompt identification and management of the SCAD. SLE was the most commonly reported rheumatological condition associated with SCAD. Prompt diagnosis and management of SCAD in such patients can be life-saving.

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Spontaneous coronary artery dissection as the first presentation of systemic lupus erythematosus

Cited by 22 publications

References 15 publications

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Spontaneous Coronary Artery Dissection in a Patient with a Family History of Fatal Ascending Aortic Dissection: Case Report and Discussion of Diseases Causing Both Presentations

Spontaneous Coronary Artery Dissection Secondary to Rheumatological Diseases: A Comprehensive Review

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