Spontaneous Coronary Artery Dissection in Patients With a Provisional Diagnosis of Takotsubo Syndrome

Hausvater, Anaïs; Smilowitz, Nathaniel R.; Ali, Thara; Espinosa, Dalisa; DeFonte, Maria; Sherrid, Mark V.; Reynolds, Harmony R.

doi:10.1016/s0735-1097(19)30642-4

Cited by 2 publications

(5 citation statements)

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“…Although it has been hypothesized that inflammation may trigger SCAD, there is mixed evidence to support this hypothesis [ 13 ]. Some studies have shown that SCAD can often be misdiagnosed as TCM [ 14 ]. Left ventricular ballooning, which is a hallmark of TCM, can be seen among SCAD patients and can be attributable to ischemia, particularly in the left anterior descending coronary territory [ 13 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

“…Some studies have shown that SCAD can often be misdiagnosed as TCM [ 14 ]. Left ventricular ballooning, which is a hallmark of TCM, can be seen among SCAD patients and can be attributable to ischemia, particularly in the left anterior descending coronary territory [ 13 , 14 ]. Conversely, awareness about TCM has also increased since the initial reports in the 1990s, originally referred to as “takotsubo” cardiomyopathy because of the classical apical ballooning reminiscent of an octopus trap [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

“…Both conditions usually present as acute myocardial infarction, or sudden cardiac death, and occur predominantly in women [ [1] , [2] , [3] , [4] ]. Given the clinical similarities and the fact that both conditions can result in acute myocardial infarction or acute coronary syndrome, there are published reports about the coexistence of these clinical entities, which raises the possibility of a potential association between the two, and underscores the need for further research [ 5 , 6 ]. Understanding whether there is a genuine association between SCAD and TCM is crucial for improving our understanding of these entities and optimizing patient care.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Spontaneous coronary artery dissection (SCAD) and takotsubo cardiomyopathy (TCM) - A potential association

Mughal,

Mirza,

Bansal

et al. 2024

American Heart Journal Plus: Cardiology Research and Practice

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Spontaneous coronary artery dissection (SCAD) and takotsubo cardiomyopathy (TCM) - A potential association

Mughal,

Mirza,

Bansal

et al. 2024

American Heart Journal Plus: Cardiology Research and Practice

View full text Add to dashboard Cite

“…A retrospective review of CAG in patients diagnosed with TTS reported that 2.5% of the cases met the criteria for SCAD diagnosis. [10] Given the many similarities in patients' demographics, clinical presentation, and predisposing stressors between SCAD and TTS, [11] co-occurrence of the 2 diseases is not accidental, and they are considered related to each other. There continues to be much chicken-or-egg debate regarding the overlap of SCAD and TTS.…”

Section: Discussionmentioning

confidence: 99%

“…These criteria make it possible to diagnose TTS in patients with pre-existing SCAD. A retrospective review of CAG in patients diagnosed with TTS reported that 2.5% of the cases met the criteria for SCAD diagnosis [10] . Given the many similarities in patients’ demographics, clinical presentation, and predisposing stressors between SCAD and TTS, [11] co-occurrence of the 2 diseases is not accidental, and they are considered related to each other.…”

Section: Discussionmentioning

confidence: 99%

A breastfeeding woman with spontaneous coronary artery dissection and possible takotsubo syndrome

Takeuchi¹,

Okada²,

Ikegami³

et al. 2021

Medicine

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Rationale: The relationship between spontaneous coronary artery dissection (SCAD) and takotsubo syndrome (TTS) remains unclear. Coexistence of SCAD and TTS has been reported in the literature. However, the relationship between these two diseases has not yet been elucidated. Patient concerns: A 36-year-old breastfeeding woman was brought to our hospital 52 days after cesarean section because of discomfort in her left arm and convulsions. Diagnoses: She was diagnosed of acute myocardial infarction (AMI). The convulsions were attributed to lethal arrhythmia. Interventions: An immediate coronary angiography revealed that her left anterior descending artery (LAD) was Type 2a SCAD, but with no flow limitation. In addition, a 12-lead electrocardiogram (ECG) revealed improvement in ST-elevation. We chose the conservative treatment according to the patient's needs. Outcomes: Conservative treatment was unsuccessful. She developed another acute myocardial infarction requiring another percutaneous coronary intervention (PCI) during hospitalization. From the course of hospitalization, we suspected the coexistence of SCAD and TTS. Lessons: When we treat patients with SCAD, we should consider the possibility of coexistence of TTS and confirm left ventricular wall motion. Patients with SCAD may require invasive treatment, hence, should be monitored for a while. An urgent strategy for managing patients with SCAD who require PCI should be established.

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Spontaneous Coronary Artery Dissection in Patients With a Provisional Diagnosis of Takotsubo Syndrome

Cited by 2 publications

References 0 publications

Spontaneous coronary artery dissection (SCAD) and takotsubo cardiomyopathy (TCM) - A potential association

Spontaneous coronary artery dissection (SCAD) and takotsubo cardiomyopathy (TCM) - A potential association

A breastfeeding woman with spontaneous coronary artery dissection and possible takotsubo syndrome

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