Recent reports in the literature indicate that incidents involving fires and explosions in the spray drying of milk products are increasing in number. While milk powder is not highly explosible, the conditions for a dust explosion, apart from the ignition source, are almost always present in certain areas of a spray drying system during its normal operation. Self‐ignition of deposits is known to be possible at the high temperatures in a spray drier. At best, this can cause product degradation and discoloration and at worst it can provide the source of ignition for an explosion. This paper is an attempt to draw together recent work on fire and explosion prevention and protection for milk powders.