Spontaneous movement after injection of propofol

Abstract

Summary Spontaneous movement following injection of propofol at induction was

Oral clonidine premedication reduces the EC50 of propofol concentration for laryngeal mask airway insertion in male patients

“…The incidence of spontaneous movements in the control group in the present study was 9%, which was comparable with 6–22% in other studies (19, 21, 22). The dose effect of propofol on spontaneous movement is controversial (20, 22). Borgeat et al.…”

“…Spontaneous movements are a relatively common side‐effect during induction of anesthesia with propofol, especially in children (19–22). The incidence of spontaneous movements in the control group in the present study was 9%, which was comparable with 6–22% in other studies (19, 21, 22). The dose effect of propofol on spontaneous movement is controversial (20, 22).…”

Metoclopramide does not influence the frequency of propofol-induced spontaneous movements

“…However, patients who had movements received significantly higher doses of propofol and lower doses of fentanyl. Similar results to those of this study were reported by Chan et al [10], who also found that higher propofol doses increased the frequency of the spontaneous movements.…”

“…A study reported that the frequency of excitatory movements was lower in patients receiving fentanyl 1.5 μg/kg [12]. Chan et al [10] reported that the use of fentanyl reduced the frequency of spontaneous movements after propofol induction. However, none of the patients who had major movements received fentanyl.…”

Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial

“…Solvent-mediated activation of the plasma kinin system leads to the production of bradykinin, in turn leading to injection site pain (Nakane and Iwama, 1999). Younger, female or Asian patients are more sensitive to propofol injection pain compared to older, male or Caucasian patients (Chan et al, 1996;Kang et al, 2010).…”