1989
DOI: 10.1007/bf01540039
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Spontaneous noncardiac chest pain: Value of ambulatory esophageal pH and motility monitoring

Abstract: We performed esophageal investigations in 20 patients suffering from noncardiac chest pain in order to assess the diagnostic value of short- versus long-term manometric and pH studies. Patients had baseline esophageal manometry with two provocative tests: a Bernstein test and an intravenous injection of edrophonium. On a separate occasion they had a 24-hr ambulatory esophageal pH and motility recording. The Bernstein test provoked chest pain in two patients, while edrophonium injection did not elicit pain in a… Show more

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Cited by 87 publications
(24 citation statements)
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“…Other causes for ischaemic-sounding chest pain are well recognized 13 . Gastro-oesophageal reflux may produce symptoms similar to angina 14 , and pH monitoring can be useful in such patients 15 . Respiratory causes are also well described, including hyperventilation resulting from anxiety 16 .…”
Section: Discussionmentioning
confidence: 99%
“…Other causes for ischaemic-sounding chest pain are well recognized 13 . Gastro-oesophageal reflux may produce symptoms similar to angina 14 , and pH monitoring can be useful in such patients 15 . Respiratory causes are also well described, including hyperventilation resulting from anxiety 16 .…”
Section: Discussionmentioning
confidence: 99%
“…Possuem baixo custo e são de fácil realização pois não necessitam de equipamentos complexos, apresentando positividade que varia de 10% a 66,6% (4,9,18,27,34,45,53) . Embora existam vários testes provocativos descritos na literatura, os mais utilizados são os testes de perfusão ácida, o do edrofônio e o da distensão esofagiana com balão.…”
Section: Discussionunclassified
“…O teste do edrofônio foi positivo em 20% dos casos, sendo descrita na literatura positividade de 14% a 55% (5,25,28,34,42,53) . No estudo de KATZ et al (34) , em 910 pacientes com DTOI, 23% apresentaram-no positivo.…”
Section: Discussionunclassified
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“…7 GERD is the most prevalent cause of NCCP, accounting for up to 60% of cases. [8][9][10][11][12] The prevalence of GERD in NCCP has been studied by pH monitoring and found to be 41% to 43%. 13,14 The cost of evaluation of NCCP is estimated to be between $315 million and $1.8 billion per year.…”
mentioning
confidence: 99%