Spontaneous osteonecrosis of the maxilla

Henien, Marianne; Patel, Vinod; Sproat, Chris; McGurk, Neck

doi:10.12968/denu.2016.43.6.563

Cited by 8 publications

(7 citation statements)

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“…Possible etiologic factors for exposed bone lesions were reported in the literature and consist of trauma, odontogenic infections, herpes zoster infection associated osteonecrosis, HIV-associated necrotizing ulcerative periodontitis, benign sequestration of the lingual plate [1], long-term corticosteroid usage [4], ischaemia, occlusion, and coagulopathies [5,6,7].…”

Section: Discussionmentioning

confidence: 99%

Idiopathic Exposed Bone Lesions of the Jaw

et al. 2019

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Introduction: Osteonecrosis of the jaw is defined as exposed bone in the oral cavity that does not heal longer than eight weeks after identification. The two most common predisposing factors for osteonecrosis of the jaw are medication-related and radiotherapy. Rarely, exposed bone in the maxillofacial region can occur due to other causes and represents a clinical and therapeutic challenge for the dentist because there is no universally accepted treatment protocol. Case presentation: We report a case of a patient with two idiopathic lesions of exposed bone which have healed after systemic antibiotic therapy, seven weeks after the first examination. Conclusion: Exposed bone lesions of the jaw are a rare entity and are poorly documented in the literature. It is necessary to exclude possible local or systemic contributing factors. Surgical and conservative therapy (antibiotics) are the treatment of choice.

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Section: Discussionmentioning

confidence: 99%

Idiopathic Exposed Bone Lesions of the Jaw

et al. 2019

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“…The causes can be divided into traumatic, non-traumatic, and idiopathic (spontaneous). Traumatic osteonecrosis is caused by thermal, mechanical, or chemical damage, while non-traumatic osteonecrosis is caused by neoplasms, infection, acquired and congenital diseases, and the use of narcotics [4]. Rare cases of idiopathic osteonecrosis have also been described [4,5].…”

Section: Other Causes Of Osteonecrosismentioning

confidence: 99%

“…Non-traumatic osteonecrosis is associated with infections, neoplasms, use of narcotics, and vascular causes such as ischemia, occlusion, coagulopathy, hemoglobinopathy, and some autoimmune diseases. However, some cases of idiopathic osteonecrosis that developed without an obvious etiological cause have also been described [4,5].…”

Section: Introductionmentioning

confidence: 99%

Osteonecrosis of the Jaw

Brzak

Aleksijević

Vindiš³

et al. 2023

Dentistry Journal

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Osteonecrosis of the jaw is a condition in which bone cells die due to various causes. It is classified as drug-induced jaw osteonecrosis, osteoradionecrosis, traumatic, non-traumatic, and spontaneous osteonecrosis. Antiresorptive or antiangiogenic drugs cause drug-induced osteonecrosis. The combination of medications, microbial contamination, and local trauma induces this condition. Osteoradionecrosis is a severe radiation therapy side effect that can affect people with head and neck cancer. It is described as an exposed bone area that does not heal for longer than three months after the end of radiation treatment with the absence of any indications of an original tumor, recurrence, or metastasis. Trauma (tooth extraction), tumor site, radiation dose that the patient receives, the area of the bone which is irradiated, oral hygiene, and other factors are risk factors for the development of osteonecrosis. Less frequently, osteonecrosis can also be induced by non-traumatic and traumatic causes. Non-traumatic osteonecrosis is brought on by infections, acquired and congenital disorders, as well as the impact of chemicals. Traumatic osteonecrosis is brought on by thermal, mechanical, or chemical damage. The treatment of osteonecrosis can be conservative, which aims to be beneficial for the patient’s quality of life, and surgical, which involves debridement of the necrotic bone.

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“…Dentro do processo fisiológico, em razão dos bifosfonatos se aderirem na hidroxiapatita da matriz óssea na cavidade oral em regiões que acontecem o processo de remodelação óssea ocorre uma indução das células osteoclásticas a sofrerem uma morte celular programada a apoptose celular (SMITH JD et al, 2016). Segundo o estudo, a mandíbula é mais susceptível a osteonecrose em virtude de apresentarem índices de vascularização diferentes em relação à maxila, consequentemente favorecendo assim seu surgimento e proliferação (HENIEN M, et al, 2016).…”

Section: Revisão Bibliográficaunclassified

A relação entre os bifosfonatos e a osteonecrose

Silva¹,

Libarino²,

Santos³

et al. 2023

Acervo Odontológico

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Objetivo: Descrever a relação entre bifosfonatos e osteonecrose na Odontologia. Revisão bibliográfica: A osteonecrose induzida pelo uso contínuo dos bifosfonatos é uma enfermidade patológica que tem como característica principal o surgimento de uma área com exposição óssea exposta na cavidade bucal. American Association of Oral and Maxillofacial Surgeons orienta aos profissionais de saúde envolvidos no tratamento da osteonecrose mandibular em estágios iniciais (I) a terapêutica se consista na utilização de enxaguantes bucais antissépticos e antibióticos para controle da infecção. Em estágios avançados (II e III) o tratamento mais invasivo é recomendado. O diagnóstico em estágio inicial da osteonecrose mandibular com um plano de tratamento adequado para o caso em questão poderá ser mais benéfico para o paciente em comparação com um diagnóstico da enfermidade em estágios avançados. No entanto, cada circunstância necessita ser tratada de forma individualizada. Considerações finais: O diagnóstico na fase inicial da osteonecrose, juntamente com um plano de tratamento adequado será benéfico ao paciente, devido o tratamento se persistir de forma mais conservadora.

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Spontaneous osteonecrosis of the maxilla

Cited by 8 publications

References 0 publications

Idiopathic Exposed Bone Lesions of the Jaw

Idiopathic Exposed Bone Lesions of the Jaw

Osteonecrosis of the Jaw

A relação entre os bifosfonatos e a osteonecrose

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