Spontaneous Pneumomediastinum

James, Molly F.; Miguel, Maria Graça; Fancher, Tonya L.

doi:10.1002/jhm.241

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…The substance most commonly associated with these serious complications requiring hospital admission is crack cocaine [4]. Binge smoking and injection of methamphetamines have also been associated with pneumomediastinum and subcutaneous emphysema, along with pneumorrhachis [5].…”

Section: Introductionmentioning

confidence: 99%

Spontaneous pneumomediastinum: A rare complication of methamphetamine use

Albanese

Gross

Azab

et al. 2017

Respiratory Medicine Case Reports

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ObjectiveTo present an unusual case of spontaneous pneumomediastinum subsequent to recreational amphetamine use.Case reportA young African American adult male was admitted to internal medicine service for treatment of rhabdomyolysis secondary to methamphetamine use. On admission, he was complaining of chest pain in addition to nausea and generalized muscle aches. By his second hospital day, chest pain had resolved yet physical exam demonstrated crepitation of the anterior chest and left axilla. Portable chest x-ray revealed subcutaneous emphysema in addition to pneumomediastinum.ConclusionSpontaneous pneumomediastinum is a rare complication of amphetamine use that is often associated with subcutaneous emphysema and can be diagnosed with chest x-ray. Management is conservative, with observation, pain control, and supplemental oxygen as needed.

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Section: Introductionmentioning

confidence: 99%

Spontaneous pneumomediastinum: A rare complication of methamphetamine use

Albanese

Gross

Azab

et al. 2017

Respiratory Medicine Case Reports

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show abstract

“…The patient was referred to the intensive care unit for follow-up, with radiography after 12 and 24 hours. Echocardiogram was inconclusive because of the poor visualization of the cardiac structures as a function of the presence of pneumo- the patient since the disease may progress with potentially fatal complications (1,(3)(4)(5) .…”

mentioning

confidence: 99%

Pneumomediastino espontâneo após esforço vocal: relato de caso

et al. 2010

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Neste estudo é relatado o caso de um paciente do sexo masculino, 14 anos de idade, que após fazer grande esforço vocal, durante uma partida de futebol, desenvolveu quadro agudo de dor torácica. As radiografias de tórax e a tomografia computadorizada evidenciaram pneumomediastino, com pequeno pneumotórax bilateral. Os exames clínico, laboratoriais e radiológicos não demonstraram qualquer fator predisponente, ficando o caso classificado como pneumomediastino espontâneo.

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Stimulants and the Lung

Tseng

Sutter

Albertson

2013

Clinic Rev Allerg Immunol

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Illicit stimulants, such as cocaine, amphetamine, and their derivatives (e.g., "ecstasy"), continue to exact heavy toll on health care in both developed and developing countries. The US Department of Health and Human Service reported over one million illicit drug-related emergency department visits in 2010, which was higher than any of the six previous years. Both inhaled and intravenous forms of these substances of abuse can result in a variety of acute and chronic injuries to practically every part of the respiratory tract, leading potentially to permanent morbidities as well as fatal consequences--including but not limited to nasal septum perforation, pulmonary hypertension, pneumothorax, pneumomediastinum, interstitial lung disease, alveolar hemorrhage, reactive airway disease, pulmonary edema, pulmonary granulomatosis, infections, foreign body aspiration, infections, bronchoconstriction, and thermal injuries. Stimulants are all rapidly absorbed substances that can also significantly alter the patient's systemic acid-base balance and central nervous system, thereby leading to further respiratory compromise. Mounting evidence in the past decade has demonstrated that adulterants coinhaled with these substances (e.g., levamisole) and the metabolites of these substances (e.g., cocaethylene) are associated with specific forms of systemic and respiratory complications as well. Recent studies have also demonstrated the effects of stimulants on autoimmune-mediated injuries of the respiratory tract, such as cocaine-induced midline destructive lesions. A persistent challenge to studies involving stimulant-associated respiratory toxidromes is the high prevalence of concomitant usage of various substances by drug abusers, including tobacco smoking. Now more than ever, health care providers must be familiar with the multitude of respiratory toxidromes as well as the diverse pathophysiology related to commonly abused stimulants to provide timely diagnosis and effective treatment.

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Spontaneous Pneumomediastinum

Cited by 4 publications

References 6 publications

Spontaneous pneumomediastinum: A rare complication of methamphetamine use

Spontaneous pneumomediastinum: A rare complication of methamphetamine use

Pneumomediastino espontâneo após esforço vocal: relato de caso

Stimulants and the Lung

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