Spontaneous Pneumomediastinum in Patients With COVID-19: A Case Series of Four Patients

Gorospe, Luis; Ayala-Carbonero, Ana María; Ureña-Vacas, Almudena; Fra-Fernández, Sara; Muñoz-Molina, Gemma María; Arrieta, Paola; Almonacid-Sánchez, Carlos; Ramos-Sánchez, Alejandro; Filigheddu, Eta; Pérez-Fernández, Manuel

doi:10.1016/j.arbr.2020.06.004

Cited by 31 publications

(29 citation statements)

References 14 publications

(18 reference statements)

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“…This severe patient was treated in the ICU and required mechanical ventilation. Although spontaneous pneumomediastinum is a rare complication of COVID-19, the mechanism of pneumomediastinum is not clear ( 27 ). These individual cases have highlighted the importance of radiologic imaging, not only in diagnosing COVID-19 pneumonia, but also in detecting accompanying complications of the disease.…”

Section: Discussionmentioning

confidence: 99%

Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumonia

Kuzan¹,

Altıntoprak²,

Çiftçi³

et al. 2021

J Turkish German Gynecol Assoc

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Objective: To describe the radiological features, diagnostic accuracy and features of imaging studies and their relation with clinical course of Coronavirus disease-2019 (COVID-19) pneumonia in pregnant women. Material and Methods: The clinical, laboratory and radiological features of symptomatic pregnant women suspected of COVID-19 were retrospectively reviewed. Chest radiography (CXR) and chest computed tomography (CT) findings of COVID-19 in pregnant women were identified. Results: Fifty-five of eighty-one pregnant women were included in the final analysis. The most common admission symptoms were dry cough (45.4%), fever (29.1%) and dyspnea (34.5%). Radiological imaging studies were performed in 34 (61.8%) patients. Fourteen (66.7%) of the laboratory-confirmed COVID-19 patients had parenchymal abnormalities on CXR, and most common abnormalities were airspace opacities (61.9%) and prominent bronchovascular shadows (28.6%). Seventeen (85.0%) of the patients had parenchymal abnormalities consistent with COVID-19 on their chest CT. Chest CT most commonly showed bilateral (88.2%), multilobe (100%) involvement; peripheral and central distribution (70.6%); patchy-shape (94.1%) and ground-glass opacity (94.1%). The sensitivity of CXR and chest CT was calculated as 66.7% and 83.3%, respectively. Preterm birth rate was 41.2% (n=7/17). Five (9.1%) of the 55 pregnant women admitted to the intensive care unit, three of those developed acute respiratory distress syndrome and one died. Conclusion: This study describes the main radiological features of symptomatic pregnant women infected with COVID-19. The refusal rate among pregnant women for the imaging modalities involving ionizing radiation was high but these had high sensitivity for COVID-19 diagnosis. The preterm birth and cesarean section rates were observed as remarkably increased.

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Section: Discussionmentioning

confidence: 99%

Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumonia

Kuzan¹,

Altıntoprak²,

Çiftçi³

et al. 2021

J Turkish German Gynecol Assoc

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“…Pneumomediastinum is an uncommon complication of COVID-19 pneumonia. Its spontaneous form has been reported in COVID-19 patients without a history of mechanical ventilation 1 . Herein, the occurrence of pneumomediastinum was likely due to a combination of barotrauma and alveolar damage due to SARS-CoV-2 infection.…”

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confidence: 85%

“…Pneumomediastinum in a patient with severe Covid-19 pneumonia Chee Yik Chang [1] [1]. Hospital Selayang, Medical Department, Selangor, Malaysia.…”

Section: Images In Infectious Diseasesmentioning

confidence: 99%

Pneumomediastinum in a patient with severe Covid-19 pneumonia

Chang

2021

Rev. Soc. Bras. Med. Trop.

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“…This mechanism may also be responsible for pulmonary edema resulting from re-expansion of a pneumothorax and edema formation in a minority of patients experiencing a severe asthma attack [16,17]. Additionally, the spontaneous occurrence of pneumomediastinum in non-intubated patients with COVID-19 may be an example of a so-called self-inflicted lung injury [18,19]. In closing, we believe that P-SILI remains an interesting hypothesis in the disease progression of COVID-19 [20].…”

Section: Lettermentioning

confidence: 99%

Conceptions of the pathophysiology of happy hypoxemia in COVID-19

et al. 2021

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In their letter-to-the-editor entitled “Misconceptions of pathophysiology of happy hypoxemia and implications for management of COVID-19”, Tobin et al. (Respir Res 21:249, 2020) debated our views on happy hypoxemia in COVID-19 (Respir Res 21:198, 2020). We thank the authors for their interesting comments and alternative viewpoints, and we would like to clarify several important aspects raised.

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Spontaneous Pneumomediastinum in Patients With COVID-19: A Case Series of Four Patients

Cited by 31 publications

References 14 publications

Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumonia

Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumonia

Pneumomediastinum in a patient with severe Covid-19 pneumonia

Conceptions of the pathophysiology of happy hypoxemia in COVID-19

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