Spontaneous Regression of an Infantile Scalp Tumor

Móles‐Poveda, Paula; Noguera, Lucero; Torrelo, Antonio

doi:10.1001/jamadermatol.2014.4985

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…Therefore, solitary and multicentric forms generally have a good prognosis even without therapy. In cases with visceral involvement, however, mortality is reported to be up to 75 % espe-cially due to cardiopulmonary or gastrointestinal complications [6,21].…”

Section: Discussionmentioning

confidence: 99%

Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate

Schubert

Wößmann

Königs

et al. 2023

Z Geburtshilfe Neonatol

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Infantile myofibromatosis is a rare benign congenital tumour that often regresses spontaneously but may pose therapeutic challenges in its widespread visceral form. We present the case of a full-term neonate with generalized infantile myofibromatosis including ubiquitous subcutaneous and muscular nodules, a tumour in the mastoid and disseminated intestinal involvement. The intestinal tumours led to a mechanical ileus with intestinal perforation within the first days of life. After partial small bowel resection and necessary proximal jejunostomy the boy was dependent on total parenteral nutrition. Chemotherapy with vinblastine and methotrexate was started and was temporarily supplemented with imatinib. Feeding stayed impossible despite tumour shrinkage. At the age of 4.5 months, restoration of intestinal continuity with further stricturoplasties was performed which – for the first time – allowed complete oral feeding. Chemotherapy was continued for further two months. Currently, the child is in good general condition with growth and further disease regression. This report suggests that massive visceral involvement of infantile myofibromatosis may require extensive intestinal surgery, as conservative therapy cannot resolve the disease and its sequelae.

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Section: Discussionmentioning

confidence: 99%

Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate

Schubert

Wößmann

Königs

et al. 2023

Z Geburtshilfe Neonatol

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“…In the infantile presentation, these tumors typically present as benign solitary lesions of the skin, subcutaneous tissue, or muscle. However, some patients are affected by a more aggressive, multicentric presentation, with lesions involving soft tissue, bone, and possibly viscera [4]. Adult myofibromas are typically characterized by a solitary lesion, located in the dermis, with benign behavior [5].…”

Section: Introductionmentioning

confidence: 99%

Adult-Onset Multifocal Cutaneous Myofibromas: A Case Report of a Rare Entity

Miller,

Lashkari,

Pokharel

et al. 2024

Cureus

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Myofibromas are observed in both infantile and adult presentations, with key differences in the number and severity of lesions between these two groups. Infantile presentations encompass both indolent, isolated cutaneous lesions, as well as aggressive, multicentric presentations with visceral involvement. Adult myofibromas appear to be characterized by a single isolated cutaneous lesion, generally asymptomatic and following a benign clinical course. The occurrence of adult multifocal myofibromas has not yet been described in the literature. Here, we report a case of a 57-year-old female who presented with two minimally symptomatic soft tissue lesions on her right leg, with the pathologic findings of each lesion consistent with a cutaneous myofibroma. This case report describes a rare presentation of adult-onset multifocal cutaneous myofibromas.

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Differential Diagnoses: Clinical and Imaging

Akhaddar

2016

Cranial Osteomyelitis

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Spontaneous Regression of an Infantile Scalp Tumor

Cited by 4 publications

References 7 publications

Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate

Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate

Adult-Onset Multifocal Cutaneous Myofibromas: A Case Report of a Rare Entity

Differential Diagnoses: Clinical and Imaging

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