2009
DOI: 10.1111/j.1346-8138.2009.00645.x
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Spontaneous regression of Merkel cell carcinoma after biopsy

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Cited by 10 publications
(6 citation statements)
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“…Since the seminal report by O' Rourke and Bell in 1986, less than 40 cases of regression of MCC have been published in the North American, Japanese and European literature . Mid‐way through the ensuing 30 years, Connelly and colleagues conducted a helpful review of the topic .…”
Section: The Clinical Prototypementioning
confidence: 99%
“…Since the seminal report by O' Rourke and Bell in 1986, less than 40 cases of regression of MCC have been published in the North American, Japanese and European literature . Mid‐way through the ensuing 30 years, Connelly and colleagues conducted a helpful review of the topic .…”
Section: The Clinical Prototypementioning
confidence: 99%
“…Regression of cutaneous Merkel cell carcinoma and nodal metastasis has rarely been reported, mostly after either surgical excision or needle biopsy of the primary lesion; and it was thought to be due to the procedures, which stimulated cell-mediated immune clearance of the residual tumor cells. [36][37][38][39][40][41][42][43][44] It is difficult to envision the spontaneous resolution of cutaneous Merkel cell carcinoma without prior medical intervention in all of our cases; moreover, it is very unlikely that all the primary tumors would have regressed without leaving any visible remnants. Therefore, we speculate that some of our nodal cases may represent primary nodal neoplasms.…”
Section: Possible Histogenesis Of Nodal Merkel Cell Carcinomamentioning
confidence: 99%
“…Spontaneous regression has been observed in other virus-associated tumors [54,55,56]. That an immune response to the MCPyV may be operational in the regression of MCC has been speculated but not established [57]. …”
Section: Clinical Coursementioning
confidence: 99%