1988
DOI: 10.1378/chest.94.4.887
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Spontaneous Regression of Squamous Cell Lung Carcinoma with Adrenal Metastasis

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Cited by 26 publications
(19 citation statements)
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“…Infection, trauma, surgery, biopsy, bleeding, and blood transfusion may elicit this immunologic reaction against the cancer. Intense medication with hormonal or immunologic agents has also been reported to be associated with spontaneous regression [6].…”
Section: Commentmentioning
confidence: 99%
“…Infection, trauma, surgery, biopsy, bleeding, and blood transfusion may elicit this immunologic reaction against the cancer. Intense medication with hormonal or immunologic agents has also been reported to be associated with spontaneous regression [6].…”
Section: Commentmentioning
confidence: 99%
“…SR seems even more uncommon in NSCLC [4,5,17]. To our knowledge only 15 cases of SR of NSCLC have been described in the literature [5][6][7][8][9][10][11][12][13][14][15][16]. The mechanisms for spontaneous regression are entirely hypothetical and the pathophysiology remains unclear.…”
Section: Discussionmentioning
confidence: 99%
“…Most of these cases concerned metastatic disease of malignancies that originated outside the thoracic cavity such as renal cell carcinoma (60%), hepatocellular carcinoma, endometrial stromal sarcoma, pleomorphic liposarcoma, esophageal cancer and leiomyosarcoma [5]. Only a few case reports described spontaneous regression of primary thoracic malignancies [5][6][7][8][9][10][11][12][13][14][15][16]. Here, we report on a case of spontaneous regression of pathologically proven non-small-cell lung cancer (NSCLC).…”
Section: Introductionmentioning
confidence: 99%
“…In the present case, there was no indication of the primary tumor. Thus, it was hypothesized that the tumor had receded as a result of spontaneous regression by apoptosis or immune-modulated destruction, following metastasis to the local lymph nodes (9,10). Alternatively, the tumor may have been too small for accurate sampling (11).…”
Section: Discussionmentioning
confidence: 99%