Spontaneous resolution of a full thickness idiopathic macular hole: fundus autofluorescence and OCT imaging

Abstract

Spontaneous closure of full thickness juxtafoveolar IMH can occur and may be properly monitored with fundus AF as well as OCT imaging.

Spontaneous closure of stage III and IV idiopathic full-thickness macular holes—a two-case report

“…Another mechanism, as presented in the case reports of Kokame and McCauley [7], Freund et al [3], Milani et al [12], and Garcia-Pous et al [4] is a bridging effect of retinal tissue across the hole.…”

“…Before the optical coherence tomography (OCT) era, the spontaneous closure of full-thickness idiopathic macular holes was also reported to happen in 5-6% of cases [5,25]. However, reviewing the literature, we found only seven case reports describing this phenomenon, observed mainly by OCT (Stratus OCT, version 3.0, Carl Zeiss Meditec, Dublin, CA, USA) [3,4,6,8,12,17,18]. In the first six cases, full-thickness macular holes with a maximum diameter of 150 μm were reported [3,6,8,17,18].…”

Spontaneous Closure of Large Base Idiopathic Full Thickness Macular Hole

“…Spontaneous closure of idiopathic full thickness macular hole secondary to release of VMT has been reported (Scassa et al 2011) and associated with Posterior vitreous detachment (PVD) (Milani et al 2007, García Fernández & Castro Navarro 2012. The case was rare and the base of the macular hole was less than 500 μm.…”

“…Complete detachment of the posterior hyaloid reduces the antero-posterior traction forces on the fovea (Ishida et al 2004). Glial cell proliferation across the macular hole and cell proliferation at the base of the macular hole (Milani et al 2007) are further theories behind the occurrence of spontaneous closure of FTMH.…”

Spontaneous Macular Hole Closure in Bilateral Macular Holes

“…1,3 In review of the literature, there have been reports of spontaneous closure of unilateral idiopathic full thickness macular holes. 4,5 We report the first case of spontaneous closure of a full thickness macular hole in one eye, after macular hole surgery in the contralateral eye in a patient with bilateral idiopathic full thickness macular holes.…”