Spontaneous Resolution of a Molluscum Sebaceum

Keratoacanthoma: a tumor in search of a classification

“…In 1889, Sir Jonathan Hutchinson described the first solitary KA as a “crateriform ulcer of the face.” 2 A myriad of synonyms have been given to KA since then, including molluscum sebaceum, 3 molluscum pseudocarcinomatosum, 4 cutaneous sebaceous neoplasm, 5 self‐healing squamous epithelioma, 6 intracutaneous cornifying epithelioma, 7 idiopathic cutaneous pseudoepitheliomatous hyperplasia, and verrugoma 8 . It was only in the late 1940s that Freudenthal of Wroclaw coined the term “keratoacanthoma,” owing to the considerable acanthosis observed in the tumor.…”

Keratoacanthoma: a distinct entity?

“…The first description of the 'crateriform ulcer of the face' was given by Jonathan Hutchinson in 1889 (1), and since then many different synonyms like molluscum sebaceum, self healing-epithelioma and keratocarcinoma have been used (2)(3)(4). In the 1940 0 s Freudenthal proposed the name Keratoacanthoma (KA) to highlight acanthosis and keratosis as major histological changes of the tumor (4)(5)(6)(7). KA however is a benign tumor, characterized by rapid growth over 4-5 weeks followed by spontaneous regression (5,8).…”

The Malignant Tumours of the Skin

“…Eook and Whimster (1950) reported on a number of these lesions under the heading of Kerato-Aoanthoma as suggested by Freudenthal. Similar terms have also been employed by Musso for Gordon (1951), Fliegelman and Loveman (1952), Whittle and Lyell (1952), Eyckmans and Eugene (1952), Beare (1953), Purdy (1953), Finley (1953) and Zoon, et al, (1953).…”