Spontaneous Resolution of a Postvitrectomy Macular Hole Retinal Detachment

Abstract

Spontaneous resolution of macular hole-associated retinal detachment in a previously vitrectomized eye has not been reported previously. Changes in tangential traction by the associated epiretinal membrane, improvement of the cystoid changes noted at the edge of the macular hole, and/or proliferation of glial tissue to bridge the hole, along with the absorption of the subretinal fluid by the retinal pigment epithelium pump contributed to this rare event have been hyphothesized.

Macular Hole Formation Followed by Spontaneous Closure After Pneumatic Retinopexy in a Patient With Diabetic Macular Edema

“…[10][11][12] These include elimination of both anterior-posterior and tangential traction with separation of the posterior hyaloid, resolution of macular cystoid changes, retinal pigment epithelial cell and glial cell proliferation, or epiretinal membrane (ERM) formation and/or progression to help cover the macular hole and promote closure. [13][14][15][16] Diabetic patients commonly have vitreoretinal interface abnormalities, which can potentially play a role in both formation of macular edema and responsiveness to anti-VEGF treatment. Eyes with DME and concurrent ERMs and/or vitreomacular traction have demonstrated poorer OCT response to anti-VEGF injections.…”

Rapid macular hole formation and closure in a vitrectomized eye following rhegmatogenous retinal detachment repair

“…[ 1 ] Degenerative changes and thinning of the macula have been reported in long-standing macula-off RRD due to hypoxia and deficiency of nutrients provided by retinal pigment epithelium–choriocapillaris complex, which may also predispose to MH formation. [ 6 7 ] This explains the fact that MH formation following RRD repair is more common in macula-off cases. [ 1 ] Similarly, our case also had a long-standing macula-off RRD with a duration of 3 months.…”