2016
DOI: 10.1016/j.joco.2015.12.004
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Spontaneous retrobulbar hemorrhage in a patient with breast cancer: A case report

Abstract: PurposeWe present spontaneous retrobulbar hemorrhage in a 52-year-old woman with history of breast cancer and tamoxifen intake which was first thought to be an orbital metastasis.Case reportA 52-year-old woman with history of breast cancer and tamoxifen intake was referred due to severe proptosis and visual loss. Orbital imaging showed an intra-conal mass. After exploration, multiple fragments of dark brown mass in the retrobulbar area were excised. Microscopic diagnosis was blood clot. All of clinical signs a… Show more

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Cited by 5 publications
(2 citation statements)
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“…2,3,8,9 Additionally, spontaneous RBH may be related to changes in coagulation, such as warfarin toxicity, heparin treatment, scurvy, idiopathic thrombocytopenic purpura, breast cancer, and systemic thrombolytic agents. [10][11][12][13][14][15][16][17] In a case series with 115 cases of spontaneous RBH presentations, about 90% of these cases were due to orbital vascular malformations, and about 10% were due to predisposing factors such as coagulopathies, hypertension, or activities that can increase strain or intra-abdominal pressure. 1 The coagulopathies examined include deep venous thrombosis, Henoch-Schonlein purpura, and elevated prothrombin and partial thromboplastin times without a specific coagulation diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…2,3,8,9 Additionally, spontaneous RBH may be related to changes in coagulation, such as warfarin toxicity, heparin treatment, scurvy, idiopathic thrombocytopenic purpura, breast cancer, and systemic thrombolytic agents. [10][11][12][13][14][15][16][17] In a case series with 115 cases of spontaneous RBH presentations, about 90% of these cases were due to orbital vascular malformations, and about 10% were due to predisposing factors such as coagulopathies, hypertension, or activities that can increase strain or intra-abdominal pressure. 1 The coagulopathies examined include deep venous thrombosis, Henoch-Schonlein purpura, and elevated prothrombin and partial thromboplastin times without a specific coagulation diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…The search phrase ‘breast cancer metastasis to the orbit’, ‘metastatic breast cancer to orbit’, and ‘orbital metastasis from breast cancer’ identified 101 cases. 3…”
Section: Methodsmentioning
confidence: 99%