Spontaneous retrobulbar hemorrhage in the setting of warfarin therapy and latent scurvy diagnosis

Chou, Brian; Rivera, Quinn N.; Francis, Courtney E.

doi:10.1080/01676830.2021.2012204

Cited by 5 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, 13%-24% demonstrate severe disability despite treatment with about 40% of these more severe cases requiring continuous immunosuppressants. 5 In our case, the patient's symptoms and inflammation resolved on IVIG and pulse-dexamethasone therapy. One year after discontinuing all treatment modalities, he is still doing well.…”

Section: Discussionmentioning

confidence: 52%

“…3 Cases of spontaneous retrobulbar hemorrhage due to underlying coagulopathy have been reported in patients with Vitamin K deficiency, dabigatran use, idiopathic thrombocytopenic purpura, hemophilia A, scurvy, and warfarin use. [4][5][6][7] The majority of reported cases are unilateral. This is, to our knowledge, the first reported case of spontaneous bilateral retrobulbar hemorrhage due to warfarin misuse.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Tendon-Sparing Extraocular Muscle Enlargement Associated With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Dimopoulos,

Barmettler

2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an inflammatory, sensorimotor polyneuropathy. It has presented with a variety of orbital and neuro-ophthalmic manifestations, including cranial nerve hypertrophy and a single case of extraocular muscle enlargement. The authors present a second case of tendon-sparing, extraocular muscle enlargement, resulting in new-onset diplopia and strabismus in a teenager with CIDP. The workup ruled out alternative causes of extraocular muscle enlargement, such as hyperthyroidism, inflammation, or malignancy. As with other cases of CIDP, management involved a combination of immunoglobulin therapy and anti-inflammatory medications. The patient experienced resolution of his symptoms, and radiologic improvement was noted in the muscle enlargement. As many CIDP patients have a favorable treatment response and long-term prognosis, awareness of this rare disease with an early and accurate diagnosis is important.

show abstract

Section: Discussionmentioning

confidence: 52%

Section: Discussionmentioning

confidence: 99%

Tendon-Sparing Extraocular Muscle Enlargement Associated With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Dimopoulos,

Barmettler

2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

show abstract

“…It must be emphasized, that all the abovementioned episodes were noted in patients without any hematological disorders, which could explain the occurrence of RH. 6 , 7 Coagulation deficiencies are well-recognized risk factors for intraorbital hemorrhage 8 , 9 , 10 ; however, there are cases of RH that are hard to explain, or at least astonishing. A serious event of bilateral retrobulbar bleeding was reported in the course of strabismus surgery and was believed to be associated with concentrated garlic intake in the form of a tablet.…”

Section: Discussionmentioning

confidence: 99%

Retrobulbar hemorrhage during strabismus surgery

Gawęcki,

Kiciński

2024

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

“…3 Cases of spontaneous retrobulbar hemorrhage due to underlying coagulopathy have been reported in patients with Vitamin K deficiency, dabigatran use, idiopathic thrombocytopenic purpura, hemophilia A, scurvy, and warfarin use. 4–7 The majority of reported cases are unilateral. This is, to our knowledge, the first reported case of spontaneous bilateral retrobulbar hemorrhage due to warfarin misuse.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Spontaneous Retrobulbar Hemorrhage due to Warfarin Misuse After Sinus Lavage

Kates,

McNelly,

Fischer

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

While warfarin has historically played an important role in anticoagulation, direct oral anticoagulants have largely supplanted warfarin due to their improved safety profile and reduced need for monitoring. Herein, the authors report the case of a 64-year-old male who developed severe, bilateral retrobulbar hemorrhage following aggressive nasal lavage due to a supratherapeutic international normalized ratio from warfarin misuse. Visual acuity on arrival was hand-motion OD and no-light-perception OS. He underwent bilateral canthotomy with upper and lower lid cantholysis before transfer to a trauma center where his international normalized ratio was greater than 12. Reversal with vitamin K and prothrombin complex concentrate was initiated. Over the course of hospitalization, vision and swelling continued to improve and at 2-month follow-up his visual acuity was 20/20 OD and no-light-perception OS. This case outlines the risk of bleeding associated with warfarin misuse and advocates for the transition of patients to direct oral anticoagulants when possible.

show abstract

Spontaneous retrobulbar hemorrhage in the setting of warfarin therapy and latent scurvy diagnosis

Cited by 5 publications

References 6 publications

Tendon-Sparing Extraocular Muscle Enlargement Associated With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Tendon-Sparing Extraocular Muscle Enlargement Associated With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Retrobulbar hemorrhage during strabismus surgery

Bilateral Spontaneous Retrobulbar Hemorrhage due to Warfarin Misuse After Sinus Lavage

Contact Info

Product

Resources

About