Spontaneous Rupture of Adenocarcinoma of Meckel’s Diverticulum- A Rare Entity

Pandiaraja, Jayabal

doi:10.7860/jcdr/2015/14110.6825

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…Carcinoid is the most common malignant neoplasm developed in MD, accounting for 33–44% of MD cases, followed by leiomyosarcoma at 18–25%, adenocarcinoma at 12–16%, and gastrointestinal stromal tumor (GIST) at 12% [ 3 ]. Although the clinical symptoms and signs of adenocarcinoma in MD are various, such as gastrointestinal bleeding [ 11 ], elevation of serum CEA and/or CA19-9 levels [ 12 , 13 ], and spontaneous rupture [ 14 ], we have found no published report of adenocarcinoma in an inverted MD with intussusception. MDs often contains heterotopic tissue such as pancreatic tissue or gastric, duodenal, jejunal, and/or colonic mucosa, which are involved in the carcinogenesis [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception

Miwa¹,

Sato²,

Hirano³

et al. 2023

surg case rep

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Background Adenocarcinoma in an inverted Meckel's diverticulum with intussusception has not been reported to date. We discuss the clinical issues concerning this rare condition and review the relevant literature. Case presentation A 71-year-old Japanese female was referred to our hospital for further investigation of severe anemia. Computed tomography revealed a tumorous lesion in the terminal ileum. Capsule endoscopy did not provide detailed images. Exploratory laparoscopy revealed intussusception in the terminal ileum. An intraluminal tumor 70 cm proximal to the ileocecal valve was observed to be the lead point. Partial resection including the tumor was performed. Macroscopically, a polypoid tumor at the tip of an inverted diverticulum-like structure was observed. The tumor was histologically composed of adenocarcinoma accompanied by gastric and pyloric gland metaplasia in the background mucosa, which was confirmed by immunohistochemical staining. Based on these characteristics, this tumor is considered to have developed from the ectopic gastric mucosa in a Meckel's diverticulum. Conclusions When we encounter patients with unfamiliar lesions in the small bowel, we need to differentiate Meckel's diverticulum related disease. Meckel's diverticulum can invert into the lumen of the small bowel and cause an intussusception, and has potential of malignant transformation.

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Section: Discussionmentioning

confidence: 99%

An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception

Miwa¹,

Sato²,

Hirano³

et al. 2023

surg case rep

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“…Most MD adenocarcinomas are diagnosed incidentally post‐operatively following resection of MD with complications, such as perforation . Preoperative diagnosis of adenocarcinoma in MD is difficult, and many cases present late as locally advanced or metastatic disease, requiring palliative resection and chemotherapy .…”

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confidence: 99%

Adenocarcinoma in a Meckel's diverticulum presenting as a phlegmon: a case report and a review of the literature

Buan

Chang

Wang

et al. 2018

ANZ Journal of Surgery

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Facing Terminal Ileitis: Going Beyond Crohn’s Disease

Goulart

Barbalho²,

Gasparini

et al. 2016

Gastroenterol Res

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Terminal ileitis (TI) is an inflammatory condition of the terminal portion of the ileum that may occur acutely with right lower quadrant pain followed or not by diarrhea, or exhibit chronic obstructive symptoms and bleeding and normally it is associated to Crohn’s disease (CD) although it may be associated to other different conditions. This review intended to contribute to a better understanding of TI in order to help in the diagnosis, medical approach and patient care. This work was performed on a survey of articles collected in different databases and a retrospective search was carried out to identify relevant studies in the field. Pathological conditions such as ulcerative colitis, the intake of non-steroidal anti-inflammatory drugs, infectious diseases, eosinophilic enteritis, malignant diseases, spondyloarthropathies, vasculitides, ischemia, sarcoidosis, amyloidosis and others may be related to ileitis but it is commonly referred to CD. To a correct therapeutic approach, it is necessary to understand the causes of this inflammation process. The performance of a clinical, laboratory, endoscopic, and histopathological evaluation of the individuals is crucial to the correct diagnosis and treatment once the inflammation of the ileum may occur due to different pathological conditions besides CD, leading to difficulties in the diagnosis. Thus, an individual approach is necessary once the correct diagnosis is crucial for the immediate therapeutic approach and recovering of the patient.

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Spontaneous Rupture of Adenocarcinoma of Meckel’s Diverticulum- A Rare Entity

Cited by 4 publications

References 12 publications

An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception

An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception

Adenocarcinoma in a Meckel's diverticulum presenting as a phlegmon: a case report and a review of the literature

Facing Terminal Ileitis: Going Beyond Crohn’s Disease

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