Spontaneous rupture of craniopharyngioma cysts. A report of five cases and review of the literature

Satoh, Hideki; Uozumi, Tohru; Arita, Kazunori; Kurisu, Kaoru; Hotta, Tsukasa; Kiya, Katsuzo; Ikawa, Fusao; Goishi, Junji; Sogabe, Takashi

doi:10.1016/0090-3019(93)90223-n

Cited by 41 publications

(41 citation statements)

References 11 publications

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“…Cases of low cholesterol content have also been reported (1). Therefore the possibility of chemical meningitis is low if the cholesterol content of the craniopharyngioma is low (4,8,9). Unfortunately, the cholesterol content cannot be estimated on MR imaging, because the protein concentration contributes more to the signal intensity than the lipid concentration on the T1-weighted image (6,10 …”

Section: Discussionmentioning

confidence: 99%

“…Chemical meningitis in craniopharyngioma is supposed to be caused by the cholesterol crystals contained in the cystic fluid (3,8). The rupture or leak result in headache, fever, nuchal rigidity, headache and photophobia (3,8). The cyst rupture can be associated with or without resolution of pressure-related symptoms (ocular finding) caused by the cyst.…”

Section: Discussionmentioning

confidence: 99%

“…The mechanism of rupture of a craniopharyngioma cyst may depend on weakness of the cyst wall caused by cyst expansion inducing degeneration of cyst wall (5). Chemical meningitis in craniopharyngioma is supposed to be caused by the cholesterol crystals contained in the cystic fluid (3,8). The rupture or leak result in headache, fever, nuchal rigidity, headache and photophobia (3,8).…”

Section: Discussionmentioning

confidence: 99%

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Recurrent chemical meningitis in craniopharyngioma without reduction in size of cyst - case report of two cases and review of literature

Rajput¹,

Srivastva²,

Kumar³

et al. 2010

Turkish Neurosurgery

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Chemical meningitis is a rare phenomenon due to rupture of a craniopharyngioma cyst; it develops because of presence of cholesterol crystals in cyst fluid secreted by the squamous epithelium lining of the cyst. Spontaneous rupture of the cyst may present with or without meningitis, depending upon the cholesterol contents of cystic fluid of tumor. A decrease in the size of cyst may or may not be noted. Here we report two cases of craniopharyngioma, one which had a recurrent episode of chemical meningitis after surgery due to leak from residual component of the craniopharyngioma without evidence of recurrence of lesion, or decrease in the size of the cyst. Another case presented with initial symptoms and signs of meningitis, with no change in the size of the lesion after the second episode of chemical meningitis. KeywOrds:Chemical meningitis, Craniopharyngioma, Rupture of craniopharyngioma cyst ÖZ Kraniofarenjioma kistinin rüptürü sonucu oluşan kimyasal menenjit nadir görülen bir fenomendir. Kraniofarenjioma kistini döşeyen skuamöz epitelin sekresyonu içinde yer alan kolesterol kristallerine karşı gelişen reaksiyon sonucu kimyasal menenjit oluşur. Kraniofarenjioma kisti rüptürü sonucu her zaman kimyasal menenjit gelişmez, kimyasal menenjit gelişimi için kist içeriğinde kolesterol kristallerinin olması gereklidir. Kist boyutlarında küçülme ile ilgili bir bilgiye rastlamamıştır. İki ayrı kraniofarenjioma olgumuzda kimyasal menenjit görüldü. İlk olgumuzda cerrahi sonrası tekrarlayan menenjit atakları görüldü. Bu görülen menenjitin tümörde rekürens olmadan direkt olarak rezidüel dokuya bağlı olduğu düşünüldü. Diğer olguda ise ilk semptom olarak menenjit ortaya çıktı, ikinci menenjit atağı sırasında yapılan kontrollerde kist çapında bir değişiklik görülmedi.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Recurrent chemical meningitis in craniopharyngioma without reduction in size of cyst - case report of two cases and review of literature

Rajput¹,

Srivastva²,

Kumar³

et al. 2010

Turkish Neurosurgery

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“…2,7) In addition, rupture of the cyst may cause cerebral infarction following vasospasm. 8) However, the quantity of cholesterol produced by cultured craniopharyngiomas varies greatly.…”

Section: Discussionmentioning

confidence: 99%

“…Only 15 reports of spontaneous cyst shrinkage due to rupture associated with craniopharyngioma are available, and many recent reports do not discuss subsequent surgical treatment. 4,[7][8][9] Spontaneous rupture of craniopharyngioma cysts without chemical meningitis are extremely rare, and the natural history after spontaneous rupture is unclear. We report two cases of spontaneous rupture of cystic craniopharyngioma without signs of chemical meningitis, followed by an increase in the cyst size after a short period of reduction.…”

Section: Introductionmentioning

confidence: 99%

Spontaneously Ruptured Craniopharyngioma Cyst Without Meningitic Symptoms. Two Case Reports.

Takahashi

Kudo

Ito

et al. 2003

Neurol. Med. Chir.(Tokyo)

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Two cases of spontaneous rupture of cystic craniopharyngioma without chemical meningitis are described. A 70-year-old woman complained of headache and visual field disturbance in July 1993. The tumor was extirpated in November 1993 and again in December 1996. After regular periodic follow-up evaluation, she was hospitalized for reoperation because of expansion of the cyst on magnetic resonance (MR) imaging in November 1998. However, preoperative MR imaging taken 8 weeks later revealed spontaneous reduction of the cyst. A 69-year-old woman noticed deteriorating vision and bitemporal hemianopsia in November 1998. The tumor was removed in December 1998, and 50.4 Gy postoperative radiotherapy was administered. MR imaging in May 2000 demonstrated an enlargement of the cyst, so she was hospitalized again for operation. However, preoperative MR imaging taken 7 weeks later showed spontaneous reduction of the cyst. Neither of the cases of cyst rupture were accompanied by symptoms of chemical meningitis. The signal intensity of the tumors on T 1 -weighted MR imaging declined after cyst reduction. Thereafter, the cysts increased in size again at 7 months and 5 months. Regular follow-up on MR imaging is necessary, since the cyst size can increase rapidly, even after spontaneous rupture.

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Molecular Targets in Craniopharyngioma

Rostami

Casar‐Borota

Gudjonsson

2020

Adult Craniopharyngiomas

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Spontaneous rupture of craniopharyngioma cysts. A report of five cases and review of the literature

Cited by 41 publications

References 11 publications

Recurrent chemical meningitis in craniopharyngioma without reduction in size of cyst - case report of two cases and review of literature

Recurrent chemical meningitis in craniopharyngioma without reduction in size of cyst - case report of two cases and review of literature

Spontaneously Ruptured Craniopharyngioma Cyst Without Meningitic Symptoms. Two Case Reports.

Molecular Targets in Craniopharyngioma

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