Spontaneous rupture of the spleen caused by a Bacillus infection: Report of a case

Abstract

We report a case of spontaneous splenic rupture (SSR) caused by a Bacillus species (sp.) infection. A 36-year-old man on warfarin therapy since an aortic valve replacement at the age of 13 was admitted to our hospital with a 3-week history of a high fever. He had been asymptomatic until 4 months previously, when he suffered a cerebral embolism despite adequate oral anticoagulation. Abdominal computed tomography revealed splenic infarctions, which resulted in splenic rupture 2 days later. After embolization of the splenic artery, splenectomy was successfully performed. Pathologic examination revealed splenic infarction, resulting from septic emboli, with associated rupture of the splenic capsule, but no abscess was found. Bacillus sp. was isolated from cultures of arterial blood preoperatively, and the excised splenic specimens, postoperatively. In addition to rupture of the suppurating intrasplenic vessels with hematoma formation, the anticoagulant therapy possibly contributed to distension of the intrasplenic hematoma.

Pancreatic adenosquamous carcinoma presenting as splenic rupture: Report of a case

“…Atraumatic splenic rupture is very rare and is associated with a variety of conditions. [7][8][9][10][11] Atraumatic splenic rupture has been already reported in leukemia 12 and in the metastatic involvement of the spleen from the lung, urinary bladder, stomach, and liver. 13,14 In association with pancreatic disease, this situation has also been reported in patients with chronic pancreatitis as a complication of splenic congestion, due to splenic vein occlusion.…”

Scientific Opinion on the maintenance of the list of QPS biological agents intentionally added to food and feed (2010 update)

“…None described toxins from QPS Bacillus species, active on human or animals. Only one publication since the previous review of the QPS list (EFSA, 2009a) concerned a human infection by a Bacillus species(Aoyagi et al, 2009). The Bacillus isolate was not identified at species level, it is therefore not possible to know if it belonged to a species of the QPS list.…”