Spontaneous spondylodiscitis: presentation, risk factors, diagnosis, management, and outcome

Kapsalaki, Eftychia; Gatselis, Nikolaos; Stefos, Aggelos; Makaritsis, Konstantinos; Vassiou, Aikaterini; Fezoulidis, Ioannis; Dalekos, George Ν.

doi:10.1016/j.ijid.2008.08.025

Cited by 74 publications

(61 citation statements)

References 21 publications

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“…[8][9][10][11][12] In our study, the main complaint of pain coincided with actual location of infected level in only five (45%) of the patients with lumbar discitis, one (25%) of the patients with dorsal discitis, and two (40%) of the patients with thoracolumbar discitis.…”

Section: Discussionmentioning

confidence: 78%

Diagnostic Difficulties in Bacterial Spondylodiscitis

et al. 2015

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Objective: To analyze aspects related to the diagnostic difficulty in patients with bacterial spondylodiscitis. Methods: Cross-sectional observational study with retrospective data collected in the period from March 2004 to January 2014.Twenty-one patients diagnosed with bacterial spondylodiscitis were analyzed. Results: Women were the most affected, as well as older individuals. Pain in the affected region was the initial symptom in 52% of patients, and 45.5% of the patients had low back pain, and those with dorsal discitis had back pain as the main complaint; the patients with thoracolumbar discitis had pain in that region, and only one patient had sacroiliac discitis. The average time between onset of symptoms and treatment was five months. The lumbar segment was the most affected with 11 cases (52%), followed by thoracolumbar in 24%, dorsal in 19% of cases and a case in the sacroiliac segment. Only seven patients had fever. Pain in the affected level was coincidentally the most common symptom. Conclusions: Early diagnosis of bacterial spondylodiscitis remains a challenge due to the nonspecific signs and symptoms reported by the patient and the wide variability of laboratory results and imaging. The basis for early diagnosis remains the clinical suspicion at the time of initial treatment.

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Section: Discussionmentioning

confidence: 78%

Diagnostic Difficulties in Bacterial Spondylodiscitis

et al. 2015

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“…24,25 Similar to septic arthritis, spondylodiscitis has an increased incidence in patients with liver cirrhosis. 26 Patients usually present with non-specific back or neck pain.…”

Section: Spondylodiscitismentioning

confidence: 99%

Cirrhosis-related musculoskeletal disease: radiological review

Arora¹,

Rajesh²,

Bansal³

et al. 2016

BJR

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Musculoskeletal problems in patients with liver disease are common; however, they are not so well described in the literature. Therefore, there is a need to collate information on these disorders, as their incidence is on a constant rise and some of these pathologies can severely debilitate the patient's quality of life. These disorders are parietal wall varices with or without bleeding, spontaneous intramuscular haematoma (e.g. rectus sheath), abdominal wall hernia, anasarca, hepatic osteodystrophy, septic arthritis, osteomyelitis, necrotizing fasciitis, osseous metastases from hepatocellular carcinoma etc. While portal hypertension plays a key role in disorders, in others, dysregulation of the coagulation system or a compromised immune system are responsible. Imaging plays an essential role in the assessment of these complications and awareness of these musculoskeletal manifestations is vital for establishing a timely diagnosis and planning of appropriate therapy, as these disorders can significantly impact the morbidity and mortality and also influence candidacy for liver transplantation. We herein comprehensively appraise various musculoskeletal complications associated with chronic liver disease/liver cirrhosis especially from an imaging perspective which, to the best of our knowledge, have not been collectively described in English literature.

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Section: Introductionmentioning

confidence: 99%

“…The source of spread of such infections is often haematogenous; however, direct spread may occur during spine surgery or an interventional procedure, such as epidural injections, nerve-root blocks or discography [2][3][4][5][6]. Primary treatment consists of systemic antibiotics, bracing and rest [2,4,7,8]. Surgery is warranted in certain clinical scenarios, such as cases refractory to conservative treatment, presence of neurological deficit, epidural abscess and progressive bony destruction with deformity or instability [2][3][4][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

“…Primary treatment consists of systemic antibiotics, bracing and rest [2,4,7,8]. Surgery is warranted in certain clinical scenarios, such as cases refractory to conservative treatment, presence of neurological deficit, epidural abscess and progressive bony destruction with deformity or instability [2][3][4][7][8][9]. Spondylodiscitis being an anterior lesion has traditionally been treated using anterior debridement with or without supplemented posterior stabilisation [3,4,[8][9][10].…”

Section: Introductionmentioning

confidence: 99%

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