Tracheal ruptures are one of the rare emergency condition in critical care patients (1). Tracheal ruptures can be formed by cervical/thoracic trauma or iatrogenic (intubation, tracheotomy, bronchoscopy, stent operations, esophagectomy, positive end expiratory pressure) or spontaneously (2,3). Spontaneous tracheal ruptures are reported by different authors in children and adults which had lung diseases, persistent cough, vomiting and chronic steroid usage (1,4-9). Corticosteroids have been widely used in the treatment of chronic obstructive lung disease (COPD) because of the antiinflammatory effects on the airways (10). The corticosteroids had many side effects including truncal obesity, acne, hyperpigmentation, hirsutism, striae, hypokalemia, myopathy, glucose intolerance, pancreatitis, mood alterations, insomnia, psychosis, headache, intracranial hypertension, hypertension, osteoporosis, adrenal insufficiency, gastrointestinal diseases, hyperlipidemia, weakness of connective tissues and myopathy (11,12). The corticosteroids decreased the hydroxyproline production, thus an inhibition on fibroblast growth and collagen synthesis which leads abnormalities on structure of the connective tissues. Also, long term corticosteroid administration induces myopathy with different pathways (11,12). In the literature repetitive spontaneous tracheal rupture was not reported. The authors report a case in which the repetitive spontaneous tracheal rupture in a patient with COPD and bronchiectasis.