Sporadic Cutaneous Keratocyst of the Scalp: A Report of an Extremely Rare Lesion

Al-Zaidi, Rana Shaker; Tantawi, Eyad; AL-Radadi, Rahaf; Banjar, Asrar

doi:10.7759/cureus.19206

Cited by 4 publications

(4 citation statements)

References 10 publications

(17 reference statements)

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“…It has been reported that AgNPs synthesized by green methods using different parts of plant extracts significantly inhibit the growth of E. coli, P. aeruginosa, S. aurous, B. cereus, and K. pneumonia, and also inhibit biofilm formation [203][204][205]. In another study, it was found that biologically synthesized ZnO NPs enhanced the antimicrobial activity and inhibited the biofilm formation by E. coli and S. aureus [206,207]. L. monocytogenes is a bacterium that causes listeriosis, a foodborne disease that increases the risk of forming biofilms in the food industry and helps the bacteria to survive in challenging environments.…”

Section: Cdse/zns Quantum Dots Dairy Product α-Lactalbuminmentioning

confidence: 98%

Nanotechnology in Food and Plant Science: Challenges and Future Prospects

Ansari

2023

Plants

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Globally, food safety and security are receiving a lot of attention to ensure a steady supply of nutrient-rich and safe food. Nanotechnology is used in a wide range of technical processes, including the development of new materials and the enhancement of food safety and security. Nanomaterials are used to improve the protective effects of food and help detect microbial contamination, hazardous chemicals, and pesticides. Nanosensors are used to detect pathogens and allergens in food. Food processing is enhanced further by nanocapsulation, which allows for the delivery of bioactive compounds, increases food bioavailability, and extends food shelf life. Various forms of nanomaterials have been developed to improve food safety and enhance agricultural productivity, including nanometals, nanorods, nanofilms, nanotubes, nanofibers, nanolayers, and nanosheets. Such materials are used for developing nanofertilizers, nanopesticides, and nanomaterials to induce plant growth, genome modification, and transgene expression in plants. Nanomaterials have antimicrobial properties, promote plants’ innate immunity, and act as delivery agents for active ingredients. Nanocomposites offer good acid-resistance capabilities, effective recyclability, significant thermostability, and enhanced storage stability. Nanomaterials have been extensively used for the targeted delivery and release of genes and proteins into plant cells. In this review article, we discuss the role of nanotechnology in food safety and security. Furthermore, we include a partial literature survey on the use of nanotechnology in food packaging, food safety, food preservation using smart nanocarriers, the detection of food-borne pathogens and allergens using nanosensors, and crop growth and yield improvement; however, extensive research on nanotechnology is warranted.

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Section: Cdse/zns Quantum Dots Dairy Product α-Lactalbuminmentioning

confidence: 98%

Nanotechnology in Food and Plant Science: Challenges and Future Prospects

Ansari

2023

Plants

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“…The test employed reagents for cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) from a French-made Ovine kit (701050) to look into the potential anti-inflammatory effects of barium oxide nanoparticles [68][69][70][71]. Nanoparticles at concentrations of 50-400 µg/mL were used to inhibit the activities of COX-1 and COX-2.…”

Section: Anti-inflammatory Assaymentioning

confidence: 99%

Multifunctional Spirogyra-hyalina-Mediated Barium Oxide Nanoparticles (BaONPs): Synthesis and Applications

Abdullah,

Rahman,

Faisal

et al. 2023

Molecules

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This research aims to biosynthesize Barium oxide nanoparticles (BaONPs) for biomedical applications, using Spirogyra hyalina as a stabilizing and reducing agent. UV–visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), energy-dispersive X-ray, X-ray diffraction (XRD), and scanning electron microscopy (SEM) were used to physiochemically characterize the barium oxide nanoparticles, while antibacterial, minimum inhibitory concentration, antifungal, free radicle scavenging, and anti-inflammatory assay were performed to assess the therapeutic potential of the synthesized BaONPs. Fourier transform infrared spectroscopy revealed bands at 615 and 692 cm−1 that corresponded to the formation of BaONPs. Scanning electron microscopy revealed the spherical and flower-shaped morphology of BaONPs having an average diameter of 64.01 ± 2.0 nm. Both Gram-positive and Gram-negative bacterial growth was halted by the barium nanoparticles, demonstrating their efficacy up to 19.12 ± 0.31 mm against E. coli, 18.83 ± 0.44 mm against Klebsiella pneumoniae, 17.31 ± 0.59 mm against P. aeruginosa, 16.56 ± 0.37 mm against S. aureus, and 15.75 ± 0.38 mm against S. epidermidis, respectively. The minimum inhibitory concentration was 9.0, 6.3, 5.5, 4.5, and 2.0 µg/mL for S. aureus, Klebsiella pneumoniae, S. epidermidis, P. aeruginosa, and E. coli, respectively. BaONPs were not that effective against fungal strains such as Rhizoctonia solani, Fusarium solani, and Fusarium proliferatum. The BaONPs exhibited potent anti-inflammatory and antioxidant activity through inhibiting cyclooxygenases type 1 (43.12 ± 1.21%) and 2 (41.23 ± 1.56%), and DPPH free radicles up to 43.52 ± 0.29% at 400 µg/mL. In conclusion, the biomolecules derived from Spirogyra hyalina have demonstrated remarkable ability to generate stable nanoparticles, offering promising prospects for their utilization as therapeutic agents and coating materials in various biomedical applications.

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“…They also increased reduced glutathione (GSH) production while reducing levels of free radicals [246]. Recently, ZnNPs synthesized using the rhizhome extract of Zingiber officinale and aqueous extract of Andrographis alata exhibited a potential anti-Alzheimer activity by inhibiting Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE) as well as antioxidative action in vitro [248,249]. Various drug (docosahexaenoic acid and osthol)-loaded ZnNPs showed promising neuroprotective effects by modulating synaptic proteins such as postsynaptic density-95 (PSD-95); synapsin-1; synaptophysin (SYP); and brain neurotransmitters such as noradrenaline, serotonin, and dopamine [250,251].…”

Section: Therapeutic Role Of Zinc-based Nps (Znnps) and Their Antioxi...mentioning

confidence: 99%

Role of Nanoparticle-Conjugates and Nanotheranostics in Abrogating Oxidative Stress and Ameliorating Neuroinflammation

Patel,

Kevadiya,

Bajwa

et al. 2023

Antioxidants

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Oxidative stress is a deteriorating condition that arises due to an imbalance between the reactive oxygen species and the antioxidant system or defense of the body. The key reasons for the development of such conditions are malfunctioning of various cell organelles, such as mitochondria, endoplasmic reticulum, and Golgi complex, as well as physical and mental disturbances. The nervous system has a relatively high utilization of oxygen, thus making it particularly vulnerable to oxidative stress, which eventually leads to neuronal atrophy and death. This advances the development of neuroinflammation and neurodegeneration-associated disorders such as Alzheimer’s disease, Parkinson’s disease, epilepsy, dementia, and other memory disorders. It is imperative to treat such conditions as early as possible before they worsen and progress to irreversible damage. Oxidative damage can be negated by two mechanisms: improving the cellular defense system or providing exogenous antioxidants. Natural antioxidants can normally handle such oxidative stress, but they have limited efficacy. The valuable features of nanoparticles and/or nanomaterials, in combination with antioxidant features, offer innovative nanotheranostic tools as potential therapeutic modalities. Hence, this review aims to represent novel therapeutic approaches like utilizing nanoparticles with antioxidant properties and nanotheranostics as delivery systems for potential therapeutic applications in various neuroinflammation- and neurodegeneration-associated disease conditions.

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Sporadic Cutaneous Keratocyst of the Scalp: A Report of an Extremely Rare Lesion

Cited by 4 publications

References 10 publications

Nanotechnology in Food and Plant Science: Challenges and Future Prospects

Nanotechnology in Food and Plant Science: Challenges and Future Prospects

Multifunctional Spirogyra-hyalina-Mediated Barium Oxide Nanoparticles (BaONPs): Synthesis and Applications

Role of Nanoparticle-Conjugates and Nanotheranostics in Abrogating Oxidative Stress and Ameliorating Neuroinflammation

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