Sporadic giant intra-abdominal desmoid tumor: A radiological case report

Kovačević, Karla; Obad-Kovačević, Dragica; Popić-Ramač, Jelena

doi:10.3892/mco.2017.1250

Cited by 10 publications

(15 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Desmoid tumors of the extremities are benign soft tissue tumors that often occur in the deep fascia, aponeurosis, and muscle. This disease is also referred to as invasive fibroma because of its local invasiveness[ 7 , 8 ]. There is a correlation between the morphology of the desmoid fibroma and its growth pattern.…”

Section: Discussionmentioning

confidence: 99%

Clinical and imaging features of desmoid tumors of the extremities

Shi¹,

Zhao²,

Jiang³

et al. 2021

WJCC

View full text Add to dashboard Cite

BACKGROUND Desmoid fibroma is a rare soft tissue tumor originating from the aponeurosis, fascia, and muscle, and it is also known as aponeurotic fibroma, invasive fibroma, or ligamentous fibroma. AIM To investigate the clinical and imaging features of desmoid tumors of the extremities. METHODS Thirteen patients with desmoid fibroma of the extremities admitted to our hospital from October 2016 to March 2021 were included. All patients underwent computed tomography (CT), magnetic resonance imaging (MRI), and pathological examination of the lesion. Data on the diameter and distribution of the lesion, the relationship between the lesion morphology and surrounding structures, MRI and CT findings, and pathological features were statistically analyzed. RESULTS The lesion diameter ranged from 1.7 to 8.9 cm, with an average of 5.35 ± 2.39 cm. All lesions were located in the deep muscular space, with the left and right forearm each accounting for 23.08% of cases. Among the 13 patients with desmoid fibroma of the extremities, the lesions were "patchy" in 1 case, irregular in 10, and quasi-round in 2. The boundary between the lesion and surrounding soft tissue was blurred in 10 cases, and the focus infiltrated along the tissue space and invaded the adjacent structures. Furthermore, the edge of the lesion showed "beard-like" infiltration in 2 cases; bone resorption and damage were found in 8, and bending of the bone was present in 2; the boundary of the focus was clear in 1. According to the MRI examination, the lesions were larger than 5 cm (61.54%), round or fusiform in shape (84.62%), had an unclear boundary (76.92%), showed uniform signal (69.23%), inhomogeneous enhancement (84.62%), and "root" or "claw" infiltration (69.23%). Neurovascular tract invasion was present in 30.77% of cases. CT examination showed that the desmoid tumors had slightly a lower density (69.23%), higher enhancement (61.54%), and unclear boundary (84.62%); a CT value < 50 Hu was present in 53.85% of lesions, and the enhancement was uneven in 53.85% of cases. Microscopically, fibroblasts and myofibroblasts were arranged in strands and bundles, without obvious atypia but with occasional karyotyping; cells were surrounded by collagen tissue. There were disparities in the proportion of collagen tissue in different regions, with abundant collagen tissue and few tumor cells in some areas, similar to the structure of aponeuroses or ligaments, and tumor cells invading the surrounding tissues. CONCLUSION Desmoid tumors of the extremities have certain imaging features on CT and MRI. The two imaging techniques can be combined to improve the diagnostic accuracy, achieve a comprehensive diagnosis of the disease in the clinical practice, and reduce the risk of missed diagnosis or misdiagnosis. In addition, their use can ensure timely diagnosis and treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical and imaging features of desmoid tumors of the extremities

Shi¹,

Zhao²,

Jiang³

et al. 2021

WJCC

View full text Add to dashboard Cite

show abstract

“…Its variable attenuation is similar or slightly higher than skeletal muscle, likely reflecting the histological contents of different combination of collagen-myxoid elements. Postcontrast enhancement on cross-sectional imaging is commonly mild to moderate and calcifications are rare [1,5].…”

Section: Discussionmentioning

confidence: 99%

“…Enhancement after administration of gadolinium contrast media is commonly seen, particularly in hypercellular regions of the tumor. The value of diffusionweighted MRI sequences is still unclear [1,5].…”

Section: Discussionmentioning

confidence: 99%

Complex Case of Aggressive Intra-abdominal Desmoid-type Fibromatosis Status Post Cholecystectomy

Rangunwala

Sitta

Prakash

et al. 2020

Cureus

View full text Add to dashboard Cite

Desmoid-type fibromatosis (DF), also known as desmoid tumor, is an extremely rare, benign, mesenchymal fibrous tumor with no potential for metastasis. It can arise from any part of the body, most commonly extra-abdominally. Intra-abdominal DF can present sporadically, in sites of previous trauma, surgical scars and irradiation, or in association with familial adenomatous polyposis and Gardner syndrome. Intra-abdominal DF is uncommon and especially rare after a common surgery like cholecystectomy. We report a rare case of a 67-year-old male who presented with a locally aggressive intra-abdominal DF in the gallbladder fossa, status post cholecystectomy. This progressively enlarging infiltrative enhancing solid mass in the gallbladder fossa on serial computed tomography and magnetic resonance imaging demonstrated gastric outlet obstruction, biliary obstruction, portal vein narrowing and encasement of hepatic artery. Diagnosis of DF in this postoperative setting was delayed and challenging due to uncharacteristic clinical presentation. Radiologists should be aware of this unusual diagnosis and spectrum of imaging findings to help in timely surgical management and planning.

show abstract

“…Mabrouk 2011 [6] F/41 Painful mass 10.9 × 5.9 × 7. Kovačević, 2017 [11] F/28 Abdominal pain 18 × 14 × 11 cm Not specific-intra-abdominal soft tissue Spleen, left adrenal gland, stomach, pancreas, hemidiaphragm, transverse colon Surgery (−) Not available Ekinci, 2017 [12] F/19 Painless mass 37 × 26 × 12 cm Pancreas Spleen Surgery (−) Not available Mahnashi, 2020 [13] M…”

Section: Follow-up/ Outcomementioning

confidence: 99%

Rib and pericardium invaded huge abdominal mass in young woman: A case report with literature review

et al. 2022

View full text Add to dashboard Cite

Rationale: Desmoid fibromatosis is a rare benign tumor, but due to its rarity and diverse clinical course, treatment guidelines have not been established. However, since a good prognosis can be expected, an accurate diagnosis and appropriate treatment are required. We describe a rare case of desmoid fibromatosis on young female that presented as huge abdominal mass.Patients concerns: A 28-year-old female with left upper abdominal pain 1 month ago was referred.Diagnoses: Abdominal computed tomography and magnetic resonance imaging revealed a heterogeneous soft tissue mass approximately 29 × 17 cm in size in the left abdomen with abdominal wall invasion and pathological fracture in costochondral junction of the left 8th to 10th ribs.Interventions: Surgical resection was performed.Outcomes: 33 × 23 × 6 cm sized tumorous mass showed proliferation of bland fibromatosis and myofibroblast with nuclear β-catenin expression on pathological examination. Desmoid fibromatosis arising from intra-abdominal soft tissue with ribs and pericardium invasion was diagnosed.Lessons: The mainstay of treatment of symptomatic desmoid fibromatosis is surgical resection, and in the case of abdominal tumor, it can be more dangerous when it invades adjacent organ. We report a case that required additionally multidisciplinary approach for surgery and postoperative treatment of huge abdominal desmoid tumor which infiltrate bone and pericardium beyond abdominal cavity.

show abstract

Sporadic giant intra-abdominal desmoid tumor: A radiological case report

Cited by 10 publications

References 11 publications

Clinical and imaging features of desmoid tumors of the extremities

Clinical and imaging features of desmoid tumors of the extremities

Complex Case of Aggressive Intra-abdominal Desmoid-type Fibromatosis Status Post Cholecystectomy

Rib and pericardium invaded huge abdominal mass in young woman: A case report with literature review

Contact Info

Product

Resources

About