Sporadic Cryptosporidium infection in Nigerian children: risk factors with species identification

Abstract

SUMMARYA cross-sectional study was conducted to investigate risk factors for sporadic Cryptosporidium infection in a paediatric population in Nigeria. Of 692 children, 134 (19 . 4 %) were infected with Cryptosporidium oocysts. Cryptosporidium spp. were identified in 49 positive samples using PCR-restriction fragment length polymorphism and direct sequencing of the glycoprotein60 (GP60) gene. Generalized linear mixed-effects models were used to identify risk factors for all Cryptosporidium infections, as well as for C. hominis and C. parvum both together and separately. Risk factors identified for all Cryptosporidium infections included malaria infection and a lack of Ascaris infection. For C. hominis infections, stunting and younger age were highlighted as risk factors, while stunting and malaria infection were identified as risk factors for C. parvum infection.

Risk Factors for Cryptosporidiosis Among Children in a Semi Urban Slum in Southern India: A Nested Case-Control Study

“…The association between malnutrition and childhood cryptosporidiosis has earlier been reported from cross-sectional studies in Mexico 15 and Nigeria. 29 Longitudinal studies from Brazil, 44 Peru, 9 and Guinea-Bissau 45 have shown that both symptomatic and asymptomatic cryptosporidiosis have an adverse and sustained impact on child growth, the effect being more protracted in younger and malnourished children. 9 Cryptosporidiosis in malnourished children has also been associated with more severe and prolonged illness than in normally nourished children.…”

Cryptosporidiosis: a neglected infection and its association with nutritional status in schoolchildren in northwestern Mexico

“…More than 20 species of Cryptosporidium are recognized, but 90% of human cryptosporidiosis is attributed to Cryptosporidium parvum and Cryptosporidiun hominis [1]. Its transmission has been associated with contaminated drinking water and food, low socioeconomic status and overcrowding conditions [2]. C. parvum has a cosmopolitan distribution and its prevalence can range from 0.1% to 31.5% in developing countries [3].…”

Hospitalização por doenças infecciosas, parasitismo e evolução nutricional de crianças atendidas em creches públicas

“…Esses resultados condizem com os de outros estudos, inclusive longitudinais, que têm reportado a influência das infecções parasitárias nos indicadores antropométricos de peso e estatura das crianças [33][34][35][36][37] . O fato de, neste estudo, o crescimento ponderal e de peso para a idade no período de um ano de frequência das crianças à creche ter sido influenciado apenas pelo adoecimento por parasitose, e não por diarreia e pneumonia, pode ter explicações relacionadas com as maiores taxas de morbidade das parasitoses e sua associação tanto com diarreia crônica quanto com pneumonia 1,31,38 .…”