Sporothrix brasiliensis: A growing hazard in the Northern area of Buenos Aires Province?

Etchecopaz, A.N.; Scarpa, Miguel; Mas, Javier; Cuestas, María Luján

doi:10.1016/j.ram.2020.02.002

Cited by 9 publications

(11 citation statements)

References 3 publications

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“…Apart from Brazil, cat-transmitted sporotrichosis was only reported recently in the North area of Buenos Aires province, Argentina, specifically in rural areas. Small outbreaks have been reported involving felines, cat owners, and even a veterinary doctor who examined a sick cat [33], proving that the spreading of the epidemic is already happening in South America. Since then, 21 cases of human sporotrichosis and 24 of feline sporotrichosis have been reported in the literature, reaching unprecedented levels, with a four-fold increase of cases of S. brasiliensis infections in humans from 2011 to 2019 [34].…”

Section: Discussionmentioning

confidence: 99%

The spread of cat-transmitted sporotrichosis due to Sporothrix brasiliensis in Brazil towards the Northeast region

et al. 2021

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Background Sporotrichosis is a worldwide subcutaneous mycosis caused by Sporothrix spp. In the past, this infection was associated with armadillo hunting, horticulturists, miners, and gardeners, being considered an implantation mycosis acquired by plant debris injury. Nevertheless, since the late nineties, it has been considered a zoonotic disease in Brazil. Here we report a case series of 121 patients with cat-transmitted sporotrichosis seen in Northeast Brazil. Methodology/Principal findings Patient’s demographic, clinical data, and length of treatment were recorded. In addition, a mycological examination and further PCR confirmation of species identification were performed. One hundred and twenty two patients were diagnosed with subcutaneous sporotrichosis from October 2016 to December 2019, while PCR revealed that 71 of them were due to S. brasiliensis. The majority of the individuals were female (n = 86; 70.5%). Patient’s age ranged from 5 to 87 years old. The clinical forms found were lymphocutaneous (58.2%) and fixed cutaneous (39.4%). Interestingly, 115 patients reported previous contact with cats diagnosed with sporotrichosis. Patients were successfully treated with itraconazole and potassium iodide. Conclusions/Significance Our study adds important contributions for the investigation of the spread of cat-transmitted subcutaneous sporotrichosis in Brazil, specifically towards the Northeast region of a continental-size country. It will also help clinicians to be aware of the existence and importance to accurately diagnose sporotrichosis and treat patients with this infectious disease in the lowest income region of Brazil.

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Section: Discussionmentioning

confidence: 99%

The spread of cat-transmitted sporotrichosis due to Sporothrix brasiliensis in Brazil towards the Northeast region

et al. 2021

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“…Brazilian health authorities have now received case notifications of CTS from 11 of 25 states in four of Brazil’s five geographical regions, with unofficially reported evidence of cases in 5 additional states [ 1 , 15 , 35 , 36 ]. Cases of CTS have also been documented in the Buenos Aires Provinces of Argentina, with evidence of increasing cases in Buenos Aires and a suspected CTS outbreak in El Calafate, Santa Cruz Province [ 12 , 14 , 37 ]. The earliest detection of S. brasiliensis in Argentina came from retrospective sampling of human and animal clinical isolates from Misiones and Buenos Aires provinces in 1986 and 1988 and soil samples from Chaco Province in 2003 [ 12 ].…”

Section: Geographic Distributionmentioning

confidence: 99%

A One Health Approach to Combatting Sporothrix brasiliensis: Narrative Review of an Emerging Zoonotic Fungal Pathogen in South America

Rossow

Queiroz‐Telles

Cáceres

et al. 2020

JoF

100

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Cat-transmitted sporotrichosis caused by Sporothrix brasiliensis has become a major public health concern and presents a distinct divergence from the traditional epidemiology of sporotrichosis. This emerging fungal pathogen spreads readily among cat populations, and human infections occur exclusively via zoonotic transmission. While sporotrichosis is an implantation mycosis that typically manifests as cutaneous lesions in humans and cats, severe extracutaneous manifestations are more common with S. brasiliensis than other Sporothrix species infections. Rapid diagnosis and appropriate treatment regimens are critical for successful clinical resolution of sporotrichosis in both cats and humans. Species-level identification of Sporothrix is possible with molecular diagnostics and necessary for tracking the geographic expansion of S. brasiliensis and better understanding its epidemiology. Combatting cat-transmitted sporotrichosis requires a One Health approach to successfully implement public health control measures.

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“…Feline sporotrichosis is caused by Sporothrix brasiliensis, S . schenckii sensu stricto, S. globosa 2 , S. humicola 3 , and S. pallida 3 , 4 , but S. brasiliensis holds the potential for zoonotic transmission of feline sporotrichosis 5 . S. brasiliensis is prevalent in South America, especially in Brazil, where the highest number of cases of feline sporotrichosis has been reported worldwide 6 .…”

Section: Introductionmentioning

confidence: 99%

First occurrence of feline sporotrichosis in a metropolitan area of Central-West Brazil

Ferreira,

Castilho,

Vargas

et al. 2024

Rev. Inst. Med. trop. S. Paulo

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Sporotrichosis is a neglected mycosis that affects human and animal hosts, including domestic cats. In Brazil, its most frequently diagnosed etiological agent is Sporothrix brasiliensis . Zoonotic transmission of S. brasiliensis occurs via direct contact between an infected cat and a susceptible human host. Notification of confirmed cases of feline sporotrichosis is not mandatory in Brazil. The metropolitan area of Goiania city can be considered a silent area for the occurrence of feline sporotrichosis. In this context, voluntary reporting of feline sporotrichosis cases is recommended for all healthcare professionals. This study aimed to report the first occurrence of S. brasiliensis in a cat from the metropolitan area of Goiania city. Cytopathology, mycology, thermal dimorphism and calmodulin gene amplification tests were performed. The mycological and molecular biological diagnoses corresponded to S. brasiliensis . The etiological agent of zoonotic sporotrichosis was detected in the metropolitan area of Goiania city, and therefore there is a risk of the emergence of new cases of cats infected with S. brasiliensis and the occurrence of zoonotic transmission of this fungus.

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Sporothrix brasiliensis: A growing hazard in the Northern area of Buenos Aires Province?

Cited by 9 publications

References 3 publications

The spread of cat-transmitted sporotrichosis due to Sporothrix brasiliensis in Brazil towards the Northeast region

The spread of cat-transmitted sporotrichosis due to Sporothrix brasiliensis in Brazil towards the Northeast region

A One Health Approach to Combatting Sporothrix brasiliensis: Narrative Review of an Emerging Zoonotic Fungal Pathogen in South America

First occurrence of feline sporotrichosis in a metropolitan area of Central-West Brazil

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