Sporotrichoid Cutaneous Infection due to Mycobacterium chelonei

Mycobacterium abscessus: a cutaneous infection in a patient on renal replacement therapy

“…There have been reports of M. abscessus infections in patients with no known risk factors, 1,13 but with an incubation period estimated to be between 16 days and 2 years (mean 30 days) the source may be difficult to identify 7 …”

Clinical microbiological case: infection imitating lymphocutaneous sporotrichosis during pregnancy in a healthy woman from the south-eastern USA

“…Skin and subcutaneous involvement is the most common early manifestation. M. fortuitum [ 3 ], M. chelonae [ 4,5 ] and M. abscessus [ 6 ] are the three main species of RGM associated with human infection. In individuals with intact immunity, cutaneous infections due to RGM are observed after traumatic implantation, following reconstructive surgery [ 7,8 ], or, rarely, as abscesses at the site of intramuscular or subcutaneous injections [ 9–11 ].…”

“…The sporotrichoid manifestation is similar to the lymphocutaneous syndrome, except that skin and subcutaneous tissue between the involved areas is frequently normal, and signs of lymphangitis are often subclinical. Pathogens associated with a sporotrichoid presentation include Sporothrix schenckii , Nocardia brasiliensis , Leishmania spp., M. leprae , M. marinum , and RGM, especially M. chelonae [ 4,5 ]. Infrequent opportunistic fungi such as Scedosporium apiospermum [ 17 ] and Paecilomyces spp.…”

Clinical microbiological case: refractory chest wall infection following reconstructive surgery in a patient with relapsed lung cancer

“…Clinically, M. tuberculosis infection is indistinguishable from infections due to RGM. In patients with skin and soft tissue infections, a plethora of acid‐fast bacilli arranged in clusters among granulocytic intradermal microabscesses is highly suggestive of a process due to M. fortuitum or M. chelonae [9–12]. Similarly, dimorphic inflammation (acute and chronic), granulocytic microabscesses and occasional non‐necrotizing granuloma are rarely seen in patients with pulmonary tuberculosis [2,13].…”