Spotted around the web: CNTNAP2 gene; post-synaptic densities; animal models

Abstract

Research roundupArabic version of the Motor Behavior Checklist has been validated for use in school settings. Research in Developmental Disabilities Neurons lacking CNTNAP2 have fewer neurites than controls do, leading to alterations in excitatory circuits. Biological Psychiatry The U.K.-based Spectrum 10K genetics study launched a three-month consultation at the beginning of March, seeking input from autistic people. Feedback from the autistic selfadvocate community led to the study being put on hold in 2021, Spectrum previously reported. Spectrum 10K Post-synaptic densities have lowered actin levels in a mouse model of fragile X syndrome. NeuronMyelin maturation and decreasing amplitude of cortical intrinsic activity characterize brain development in adolescents, as measured by functional MRI. Nature Neuroscience NeuronChat is a computational tool that combines spatially resolved transcriptome measures with a database of molecular interactions between neurotransmitters and their targets to characterize neuronal pathways. Nature Communications A protein delivery system, derived from a bacterial tool, can be engineered to target human cells. Nature Autistic adults have more difficulty comprehending metaphors than do non-autistic adults, according to a small study. Journal of Autism and Developmental Disorders Diagnostic instruments for autism are not intended to provide a final answer but to contribute information that may guide clinical care.