Spray drying of Eugenia dysenterica extract: effects of in-process parameters on product quality

Abstract

A 2³ full factorial design was used to assess the impact of spraying air flow rate (30-50 L/min), drying air inlet temperature (90-150 ºC) and extract feed rate (4-6 g/min) on the quality of Eugenia dysenterica DC., Myrtaceae, spray-dried extracts. Response surface methodology (RSM) was applied to analyze the significance of the effects of process factors on product quality and to obtain fitted equations to predict dry powder properties. Powder yields were satisfactory, ranging from 34.64 to 63.92%. The dried products showed moisture contents and water activities below 5% and 0.5, respectively. The recuperation ratios of total polyphenols, tannins and flavonoids ranged from 88.66 to 99.07%, 70.38 to 81.87% and 74.51 to 98.68%, respectively. Additionally, in some conditions the parameters related to dry product’s flowability and compressibility varied over a range acceptable for pharmaceutical purposes. RSM proved that studied factors significantly affected most of the quality indicators at different levels. The spray drying technology is an attractive and promising alternative for the development of intermediate phytopharmaceutical products of E. dysenterica

Effects of Spray-Drying Temperatures and Carriers on Physical and Antioxidant Properties of Lemongrass Leaf Extract Powder

“…When the temperature elevated from 110 • C to 150 • C, TPC was reduced from 3.02 to 2.12 mg GAE/100 g DW. The highest TPC was achieved at 110 • C and the lowest one was collected at 150 • C. Similar observations were found in a research of Misha et al [34] of which the TPC of amLa juice powder decreased from 250 to 150 mg GAE/100 g DW when spray-drying inlet temperature increased from 125 • C to 175 • C.…”

Dry Powder Formulation From Physalis Peruviana L. Fruits Extract With Antidiabetic Activity Formulated via Co-Spray Drying

“…The analysis of this behavior is widely detailed in the scientific literature [18,23,25,[37][38][39][40]. These results agree with Souza et al [18], in this research the evaporation capacity in SD process depends on the inlet temperature and feed rate (pump setting) and are determining factors in the moisture content of Bauhinia forficata extract.…”

“…However, due to an increase in temperature, the response variable produces samples with smaller particle size, possibly due to the evaporation of ethanol before they are formed from larger droplets. Some authors [25,36,39] found similar results.…”

“…These results agree with Souza et al [18], in this research the evaporation capacity in SD process depends on the inlet temperature and feed rate (pump setting) and are determining factors in the moisture content of Bauhinia forficata extract. On the other hand, several authors have found that the inlet temperature at its upper level has a negative influence on the moisture content for different extracts [36,[39][40][41][42][43].…”

Eugenia dysentericaDC. (Myrtaceae) exerts chemopreventive effects against hexavalent chromium-induced damagein vitroandin vivo

“…The lyophilized hydroalcoholic extract (yield: 19.5%, w/w) was obtained through the percolation of leaf powder (1 kg) in ethanol:water solution (70:30, v/v), standardized by determination of its major phytochemical markers (3.45% and 53.7% of tannins and flavonoids, respectively) and used for developing of a product via spray drying, as previously described by our research colleagues (Couto et al 2009(Couto et al , 2011(Couto et al , 2012(Couto et al , 2013.…”