Spurenelemente in menschlichem Fruchtwasser*

Thieme, R; Schramel, P.; Mahr, W.

doi:10.1055/s-2008-1037216

Cited by 7 publications

(4 citation statements)

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“…The amniotic fluid zinc concentrations at term determined in this study do not agree with any of the data given in the literature (8,9,14,15,17,18,(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31). Figure 5 shows a detailed comparison.…”

Section: Biscussioncontrasting

confidence: 71%

“…instrumental neutron activation analysis äs the method of detection. At an early stage of this study it became clear that our results were considerably lower than any of the values given in the literature (8,9,(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31). Thus, in order to provide support for our own results it was essential to devote more attention to the determination of amniotic fluid zinc than was originally intended.…”

contrasting

confidence: 67%

“…The analytical conditions described in the literature for the zinc determination in amniotic fluid contain widely varying procedures for the pre-treatment of the samples. They include recommendations for measuring without treating the sample (8, 9, 19, 21-23), after 1: 10 dilution with distilled water (14,15), after filtration (24, 27-29), after centrifugation (25,26,30), after centrifugation of turbid samples (16)(17)(18) and after precipitation with trichloroacetic acid and centrifugation (31).…”

Section: Comparison Of Determination Methods: Instrumental Neutron Acmentioning

confidence: 99%

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Determination of Zinc in Amniotic Fluid in Normal and High Risk Pregnancies

Rösick¹,

Rösick²,

Βrätter³

et al. 1983

CCLM

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Summary:Taking the necessary precautions essential for accurate trace element analysis, the zinc concentrations of 227 samples of amniotic fluid taken at term were determined by means of neutron activation analysis. Half of the zinc was found to be bound to the particles present in amniotic fluid. In the control group (123 cases) the zinc concentrations ranged from 25-261 g/l for untreated samples and from 14-143 g/l when the samples were centrifuged for 10 min at 22000g prior to analysis. The values showed log-normal frequency distributions and were lower than any of the values published in the literature to date.No statistically significant differences could be found, when zinc concentrations of various risk groups (mothefs suffering from gestosis or diabetes mellitus, newborns hypo-or hypertrophic, twin births) were compared with the zinc concentration of the control group. The amniotic fluid zinc concentration is not, therefore, a suitable indicator for the diagnosis of distufbances of the embryonic development.

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Section: Biscussioncontrasting

confidence: 71%

contrasting

confidence: 67%

Section: Comparison Of Determination Methods: Instrumental Neutron Acmentioning

confidence: 99%

See 1 more Smart Citation

Determination of Zinc in Amniotic Fluid in Normal and High Risk Pregnancies

Rösick¹,

Rösick²,

Βrätter³

et al. 1983

CCLM

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“…Pre-irradiation separation procedures have been described which eliminate the interfering activities of chlorine and sodium in the instrumental analysis of biological samples in order to determine the short-lived radionuclides of the elements Al, Br, Cu, Mg, Μη, Κ and V [47], Nevertheless, it has to be pointed out that all pre-irradiation treatments of the samples bear the risk of contamination, especially if the elements to be determined are present in the ultra trace range (as it is the case for various elements in biological fluids). At the ppb-level serious contamination problems exist not only in the preparation step but often in the course of collection and storage of the samples [48][49][50][51]. On the other hand, the risk of element losses in the pre-irradiation treatment of biological materials also has to be taken into consideration, as mentioned above.…”

Section: Procedures Of Neutron Activation Analysismentioning

confidence: 99%

On the Application of Neutron Activation Analysis in the Life Sciences

Βrätter¹

1983

Radiochimica Acta

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Amniotic fluid zinc in risk pregnancies

Laitinen

Siimes

Vgori

et al. 1984

Biol Trace Elem Res

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The zinc concentration of amniotic fluid (AF) of 129 pregnant women was analyzed by the flame atomic absorption spectrometry. This prospective study was performed in order to find out whether the determination of the AF zinc concentration can be used to monitor the growth and development of the fetus. There were two groups of patients: early stage (15th-19th gestation wk) in which the amniocentesis was performed as a prenatal genetic examination, and late stage (26th-40th wk) in which the amniocentesis was performed due to obstetric reasons. The average AF zinc concentrations were 1.2 and 1.0 μmol/L in the early and late gestation group, respectively. The AF zinc concentration did not correlate with the weight, height, or Apgar scores of the newborn nor with the maternal diseases, age, or parity. The AF zinc concentration in the late gestation group was significantly lower if the fetus was male than if it was female. If the AF was greenish the zinc concentration was elevated. One malformation, congenital nephrosis, with an exceptionally high zinc concentration (9.0 μmol/L), was found.

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Spurenelemente in menschlichem Fruchtwasser*

Abstract: By means of NAA 14 trace elements yet unknown in the human amniotic fluid were studied. The results seem to support the hypothesis that Rb and Br are essential trace elements.

Cited by 7 publications

References 0 publications

Determination of Zinc in Amniotic Fluid in Normal and High Risk Pregnancies

Determination of Zinc in Amniotic Fluid in Normal and High Risk Pregnancies

On the Application of Neutron Activation Analysis in the Life Sciences

Amniotic fluid zinc in risk pregnancies

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