Sputum induction for assessment of lower airway infection in preschool children

Jochmann, Anja; Robson, K; Fleming, Louise; Artusio, Luca; Nagakumar, Prasad; Bush, Andrew; Saglani, Sejal

doi:10.1183/13993003.congress-2015.pa1316

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, young children under the age of 6 years are typically unable to expectorate and hence require oropharyngeal suctioning to obtain an induced sputum sample. Sputum samples obtained by induction in this age group are superior to an oropharyngeal swab in young children with CF 14 but have very modest sensitivity and specificity compared to bronchoalveolar lavage 15 and risk false positive cultures due to contamination from the upper airway 16 ‐With the increased access to modulator therapy a greater percentage of people with CF may not be spontaneously productive and the use of sputum induction in CF clinical practice may increase to facilitate ongoing microbial surveillance. …”

Section: Indications For Sputum Inductionmentioning

confidence: 99%

Thoracic Society of Australia and New Zealand position statement: The safe clinical use of sputum induction for bio‐sampling of the lower airways in children and adults

Schultz,

Balaguruswamy,

Dentice

et al. 2024

Respirology

View full text Add to dashboard Cite

Sputum induction is widely used in clinical settings for collection of biological samples from the lower airways. However, in recent years sputum induction has been associated with serious adverse events and even death. This position statement was commissioned by the Thoracic Society of Australia and New Zealand to address major adverse events of two deaths associated with sputum induction that have occurred in Australia in 2021, and outlines best practice for the safe use of sputum induction. The statement resulted from systematic literature searches by a multi‐disciplinary group including respiratory physicians, nurses and physiotherapists (paediatric and adults focused). Consumers had input to an advanced draft of the position statement. The position statement covers indications for sputum induction, informed consent, scope of practice of personnel administering the procedure, infection control considerations, details about the sputum induction procedure, safety considerations and risk assessment in clinical settings.image

show abstract