Squamous carcinoma of the head and neck: cured fraction and median survival time as functions of age, sex, histologic type, and node status

Gamel, John W.; Jones, A. S.

doi:10.1038/bjc.1993.196

Cited by 23 publications

(13 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…19 -23 Females tended to have a better prognosis than males, as was also seen in a large Norwegian study 21 but not in earlier studies. 19,20,22,23 The prognostic value of margin status in surgically treated patients has been reported frequently for a variety of cancers. 24,25 In cases of head and neck cancer, tumor positive surgical margins are also highly correlated with a poor prognosis, despite the use of postoperative radiotherapy to treat these patients.…”

Section: Discussionmentioning

confidence: 99%

The impact of nutritional status on the prognoses of patients with advanced head and neck cancer

Schueren¹,

Leeuwen²,

Kuik³

et al. 1999

Cancer

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

The impact of nutritional status on the prognoses of patients with advanced head and neck cancer

Schueren¹,

Leeuwen²,

Kuik³

et al. 1999

Cancer

View full text Add to dashboard Cite

“…We know that the tumor N stage before therapy had a prognostic impact, 14 so the criterion of patients included in this study was absence of metastasis to determine whether expression of c-Myc and expression of Bcl-2 are independent prognostic indicators.…”

Section: Commentmentioning

confidence: 99%

Significance of c-Myc and Bcl-2 Protein Expression in Nasopharyngeal Carcinoma

Yu¹,

Dong²,

Li³

et al. 2003

Arch Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…6 The fact that older people had significantly poorer five-year survival from tongue cancer may be due to a number of factors including delay in diagnosis, poorer nutritional and immunological status and reduced ability to withstand aggressive treatment modalities such as radiotherapy or surgery. 21,22 Many studies have specifically addressed the relationship between age and prognosis for tongue SCC and offered conflicting conclusions. Some studies have reported that younger age was associated with poor prognosis; 22,23 others have found it to be a positive prognostic influence, 24,25 or to have no influence at all.…”

Section: 17mentioning

confidence: 99%

“…21,22 Many studies have specifically addressed the relationship between age and prognosis for tongue SCC and offered conflicting conclusions. Some studies have reported that younger age was associated with poor prognosis; 22,23 others have found it to be a positive prognostic influence, 24,25 or to have no influence at all. 26,27 Some authors have proposed that the patient population regarded as 'young' patients with oral SCC (generally defined as less than 35 or 40 years of age) may be composed of several subsets of patients with variable clinical course.…”

Section: 17mentioning

confidence: 99%

Epidemiological analysis of tongue cancer in South Australia for the 24‐year period, 1977–2001

Lam

Logan

Luke³

2006

Australian Dental Journal

View full text Add to dashboard Cite

(Accepted for publication 13 July 2005.) INTRODUCTIONTongue cancer is the most common intra-oral malignancy in Western countries. It accounts for between 20 to 50 per cent of all malignancies involving the oral cavity.1 More males than females are affected and the highest incidence occurs in the seventh decade of life.1,2 The vast majority of tongue malignancies, more than 95 per cent, are squamous cell carcinomas (SCC).1,2 The lateral border and the base of the tongue are the most commonly involved sub-sites of the tongue. Indeed in some studies, the base of the tongue accounts for up to one-third of all SCC of tongue. 3 The aetiological agents that are considered most important with respect to SCC of the tongue include tobacco (smoking and chewing habits) and alcohol consumption. 1,2The incidence and mortality of the disease varies between different geographic areas. There has been a reported increased incidence of tongue SCC and associated mortality over recent decades in Europe and the United States. 2,4,5 Additionally, an increased incidence of SCC of the tongue in young adults has been reported from studies conducted in several countries.2-6 Approximately 5-10 per cent of cases of tongue cancer occur in younger patients, many of whom do not have the identified risk factors such as smoking and alcohol. 6 Debate continues in the literature regarding the aetiology, tumour biology and prognosis of tongue cancer in young patients.In spite of advances in cancer therapy, the worldwide trend in five-year survival rates of tongue SCC since the early 1970s has remained relatively constant,

show abstract

Squamous carcinoma of the head and neck: cured fraction and median survival time as functions of age, sex, histologic type, and node status

Cited by 23 publications

References 14 publications

The impact of nutritional status on the prognoses of patients with advanced head and neck cancer

The impact of nutritional status on the prognoses of patients with advanced head and neck cancer

Significance of c-Myc and Bcl-2 Protein Expression in Nasopharyngeal Carcinoma

Epidemiological analysis of tongue cancer in South Australia for the 24‐year period, 1977–2001

Contact Info

Product

Resources

About