1994
DOI: 10.1006/gyno.1994.1272
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Squamous Cell Carcinoma Antigen: Clinical Utility in Squamous Cell Carcinoma of the Uterine Cervix

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Cited by 86 publications
(52 citation statements)
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“…Serum SCC concentration has a sensitivity between 56% and 86% and specificity between 83% and 100% for detecting recurrent squamous cell cervical cancer (386,388,392,396,398,401,407,409,412 ). With the use of SCC, a lead time of up to 14 months for detecting recurrent disease has been reported, with a mean or median between 2 and 6 months (386, 388, 396 -398, 400, 401, 403, 405, 407 ).…”
Section: Use Of Scc In Monitoring Response To Treatment and Early Detmentioning
confidence: 99%
“…Serum SCC concentration has a sensitivity between 56% and 86% and specificity between 83% and 100% for detecting recurrent squamous cell cervical cancer (386,388,392,396,398,401,407,409,412 ). With the use of SCC, a lead time of up to 14 months for detecting recurrent disease has been reported, with a mean or median between 2 and 6 months (386, 388, 396 -398, 400, 401, 403, 405, 407 ).…”
Section: Use Of Scc In Monitoring Response To Treatment and Early Detmentioning
confidence: 99%
“…Several studies show that increased serum SCCA levels correlate with the extent of disease in patients with cervical SCC (Kato and Torigoe 1977;Senekjian et al 1987;Duk et al 1990;Bolli et al 1994). For example, the incidence of elevated pretreatment serum SCCA levels range from 33% in Stage IB to 93% in Stage IV disease (Kato 1992).…”
mentioning
confidence: 99%
“…Serum concentrations of this marker correlate well with clinical stages of the disease, the presence or absence of risk factors, the effect of treatment and the course of the disease. [4][5][6] Furthermore, in SCC of the lung, cervix, head and neck or esophagus, the SCCA values were related to tumor stage [7][8][9][10] and were highest in patients with metastases. 11 Cloning of the SCCA cDNA demonstrated that it belongs to the family of serine protease inhibitors (serpins).…”
Section: Introductionmentioning
confidence: 95%