Squamous cell carcinoma arising in residual odontogenic cyst

Schwimmer, Alan; Aydın, Faruk; Morrison, S.

doi:10.1016/0030-4220(91)90167-b

Cited by 38 publications

(21 citation statements)

References 9 publications

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“…Since most reports present isolated cases only, the prognosis is difficult to evaluate. The reported 2-year-survival rates lie between 53 and 63% (Eversole et al, 1975;Schwimmer et al, 1991) whilst for the 5-year-survival, figures are 30-40% Thomas et al, 2001). The aetiological factors that initiate transformation of cystic epithelium are unknown, although infection has been implicated (Gardner, 1969).…”

Section: Discussionmentioning

confidence: 88%

“…Primary intraosseous carcinoma is far more common in the mandible than in the maxilla (Zwetyenga et al, 2001) and metastasis to cervical lymph nodes is observed in up to 50% of all cases (Manganaro et al, 1997;Eversole, 1999). Primary intraosseous carcinoma arising from odontogenic cysts affects men twice as often as women, the median age being 57 years (Gardner, 1969;Schwimmer et al, 1991). Since most reports present isolated cases only, the prognosis is difficult to evaluate.…”

Section: Discussionmentioning

confidence: 98%

“…In most of the cases, the margins are irregular or poorly defined (Eversole et al, 1975;Schwimmer et al, 1991;Dayal and Rawal, 1997), although they may also appear clearly defined (Suei et al, 1994;Eversole, 1999).…”

Section: Article In Pressmentioning

confidence: 95%

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Primary intraosseous carcinoma of the jaws arising from an odontogenic cyst – a case report

Scheer

Koch

Drebber

et al. 2004

Journal of Cranio-Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 98%

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Primary intraosseous carcinoma of the jaws arising from an odontogenic cyst – a case report

Scheer

Koch

Drebber

et al. 2004

Journal of Cranio-Maxillofacial Surgery

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“…Post operative radiation therapy is recommended and was given to both our cases. Two year survival rates are reported as 53-63 % [24,25]. Some authorities believe that carcinomatous change is the only indication for resection, stating that resection with its morbidity may be too radical and represent an overtreatment of a benign lesion [26].…”

Section: Discussionmentioning

confidence: 99%

Keratocystic Odontogenic Tumor (KCOT/OKC)—Clinical Guidelines for Resection

Warburton

Shihabi

Ord

2015

J. Maxillofac. Oral Surg.

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Purpose There is no clinical consensus for the treatment of Keratocystic Odontogenic Tumor (KCOT). KCOTs are regarded as benign aggressive tumors and resection is usually considered as a last option. We review the clinical indications for resection based on a case series. Methods This is a retrospective study of patients with KCOT treated in a single unit over 17 years. Eighty patients were identified, of which 12 (15 %) underwent resection. The remaining 68 patients were managed by enucleation and curettage, enucleation with peripheral ostectomy, or decompression with secondary enucleation. Data extracted includes gender, age, race, location, previous treatment for the lesion, surgery and outcome/ follow up. Results Twelve patients treated by resection were identified. The location in the ten benign resected KCOTs was either the mandibular ramus or the posterior maxilla. All mandibular KCOTs exhibited perforation of the lingual plate and involvement of the pterygoid musculature. Seven of the ten cases were recurrent KCOTs and three had no prior treatment. Two had malignant changes in the KCOT and were also resected. Conclusion The primary reason for resection of KCOT was involvement of the pterygoid muscles. The presence of malignant change was a separate indication for resection.

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“…The 2-year survival rate from all SCCAs is between 53% and 63%. [36811] A malignant change in odontogenic keratocysts (OKC) has been rarely reported. In a review of the literature, only 15 reports of SCCA developing from OKCs were found.…”

Section: Introductionmentioning

confidence: 99%

Squamous cell carcinoma in a maxillary odontogenic keratocyst: A rare entity

Maria

Sharma²,

Chhabria

2011

Natl J Maxillofac Surg

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Odontogenic cysts in the maxilla are common but a malignant change in an odontogenic cyst is a comparatively a rare occurrence; however, these entities present with clinical and radiographic features similar to benign, expansible, central, odontogenic tumor, or cyst of the jaws. A patient reporting with squamous cell carcinoma arising from an odontogenic keratocyst of right maxilla has been worked up clinically, radiographically, and pathologically. The case was surgically managed and followed up. A 54-year-old male patient with a compressible, rapidly growing swelling of right maxilla was clinically diagnosed to be a case of odontogenic cyst. On radiologic examination it appeared similar to a cystic lesion. An incisional biopsy obtained from the cyst wall showed it to be odontogenic keratocyst with histologic evidence of malignant transformation. The pathogenesis of the tumor, the biologic progression, and prognosis and overall clinical and histopathogical features of this rare malignancy is reported and discussed.

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Squamous cell carcinoma arising in residual odontogenic cyst

Cited by 38 publications

References 9 publications

Primary intraosseous carcinoma of the jaws arising from an odontogenic cyst – a case report

Primary intraosseous carcinoma of the jaws arising from an odontogenic cyst – a case report

Keratocystic Odontogenic Tumor (KCOT/OKC)—Clinical Guidelines for Resection

Squamous cell carcinoma in a maxillary odontogenic keratocyst: A rare entity

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