Squamous cell carcinoma (Bowen’s disease) in situ in three cats

Conceição, Lissandro Gonçalves; Camargo, Luciane Pires de; Costa, P.R.S.; Kuwabara, D.A.; Fonterrada, C.O.

doi:10.1590/s0102-09352007000300039

Cited by 2 publications

(4 citation statements)

References 8 publications

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“…1,3 D cati mites have also been identified at lesional sites of Bowenoid in situ carcinoma (BISC). 23,24 Although crusting nasal dermatitis can be a sign of BISC, in this case, the absence of hyperkeratotic, hyperpigmented, crusted plaques or papules on the skin did not support such a diagnosis. 23,25 The lack of pigment at the lesional site in this cat, along with the history of outdoor activity, initially raised the suspicion of solar-induced lesions.…”

Section: Discussionmentioning

confidence: 64%

Effectiveness of a fluralaner spot-on formulation in a case of feline demodicosis due to Demodex cati

Bouza-Rapti

Tachmazidou

Farmaki

2022

Journal of Feline Medicine and Surgery Open Reports

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Case summary A 7-year-old male domestic shorthair cat was presented with a non-pruritic erythematous crusted nasal hypotrichosis along with bilateral ceruminous otitis externa. The cat was diagnosed with diabetes mellitus and was positive for feline immunodeficiency virus (FIV). Deep skin scraping, trichograms from lesional skin and ear canal parasitological examination were positive for Demodex cati. A 250 mg (55.5 mg/kg) fluralaner spot-on for medium-sized cats (Bravecto; MSD) was applied to the base of the cat’s head. Re-examinations were carried out on the fourth, sixth and eighth weeks after therapy. On the fourth week, the ceruminous otitis had resolved completely and the nasal lesions were markedly improved. One dead adult D cati was found in deep skin scrapings while other tests from the skin and both ear canals were negative. On the second re-examination only a mild hypotrichosis persisted on the nasal region and all parasitological examinations were negative. Eight weeks after the initial examination, the skin lesions had almost clinically resolved. On the 12th week, fluralaner spot-on was repeated. No recurrence was noted at the 6-month follow-up. Relevance and novel information The use of isoxazolines has been reported for only a few demodectic cats but was described to be safe and effective. This is the first report to evaluate the efficacy of a single spot-on fluralaner for the treatment of localised dermatitis and otodemodicosis due to D cati, and suggests it as an effective, safe and practical treatment.

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Section: Discussionmentioning

confidence: 64%

Effectiveness of a fluralaner spot-on formulation in a case of feline demodicosis due to Demodex cati

Bouza-Rapti

Tachmazidou

Farmaki

2022

Journal of Feline Medicine and Surgery Open Reports

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“…Other factors such as age, gender, breed, coat, and exposure to some types of viruses may be linked (3).…”

Section: Discussionmentioning

confidence: 99%

“…Although the etiology of BISC is still unknown, there are indications of viral involvement, either by papillomavirus or others, according to hypotheses presented by Conceição et al (3). In case report 1, the feline was FIV positive, a condition associated with low immunity, in addition to the loss of regulatory control over cell multiplication, leading to morpho-functional changes in cells that conferred dorsoventrally elongated nuclei, inclined in the same direction (windblow) and atypical, multilobular nucleoli, with clusters of chromatins that may or may not be present.…”

Section: Discussionmentioning

confidence: 99%

“…The cats in this study were in an advanced state of progression of the lesions, making surgical excision impossible, mainly due to their location. The lesions' location in areas with little hair and in the head region make the surgical approach difficult due to the lack of margin for the procedure (3,5). Therefore, non-invasive techniques become treatment options.…”

Section: Discussionmentioning

confidence: 99%

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Late diagnosis of Bowenoid in situ carcinoma in two cats: the importance of identifying mild and superficial lesions

Martins,

Moraes,

Romani

et al. 2024

BJVP

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Cutaneous neoplasms have a significant representation in the casuistry of neoplasms in felines, emphasizing squamous cell carcinoma and basal cell carcinoma. Thus, clinical knowledge is necessary for the correct diagnostic and curative approach to the patient. This study aimed to report two cases of late diagnosis of Bowenoid carcinoma in adult cats (> one year) admitted at the Veterinary Teaching Hospital of the Federal University of Jataí in order to collaborate with the existing literature and help veterinarians in the knowledge of associated lesions. At macroscopy in the hospital admission, both cats presented lesions on the head in the bilateral supraorbital frontal region that slowly evolved into erosions and crusted ulcers with purulent exudation, in addition to lesions in the perilabial region (case 1). In microscopy, findings revealed Bowenoid carcinoma in situ. Supraorbital lesions revealed the abrupt formation of epidermal plaques, including follicular infundibulum continuous with the acanthotic epidermis with loss of normal stratification. Focal orthokeratosis and marked atypia of keratinocytes (macrokaryosis, macronucleosis, macrocytosis, anisokaryosis, and anisocytosis) were also observed. Early diagnosis through clinical analysis combined with histopathological evaluation is of fundamental importance to ensure therapeutic success, improving the patient’s prognosis, a condition not achieved in the cases presented mainly due to late diagnosis.

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Squamous cell carcinoma (Bowen’s disease) in situ in three cats

Cited by 2 publications

References 8 publications

Effectiveness of a fluralaner spot-on formulation in a case of feline demodicosis due to Demodex cati

Effectiveness of a fluralaner spot-on formulation in a case of feline demodicosis due to Demodex cati

Late diagnosis of Bowenoid in situ carcinoma in two cats: the importance of identifying mild and superficial lesions

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