Squamous Cell Carcinoma Developing from an Epidermoid Cyst of the Ear

Abstract

The authors have indicated no significant interest with commercial supporters.

A Case of an Undifferentiated Squamous Cell Carcinoma Arising from an Epidermal Cyst

“…The nature of the stimulus for malignant transformation in an epidermal cyst is uncertain [3]. It has been suggested that chronic irritation of the lesion could be a triggering factor [2].…”

“…It has been suggested that chronic irritation of the lesion could be a triggering factor [2]. Also there is growing evidence that human papillomavirus (HPV) infection may play a role in the development of nonmelanoma skin cancer [3, 4]. …”

“…Primary treatment for a neoplastic cystic lesion is wide excision with adequate margin [3]. It is proposed that minimal margins of excision are 4 mm for all but high-risk tumors, for which at least a 6 mm margin is recommended [3].…”

“…It is proposed that minimal margins of excision are 4 mm for all but high-risk tumors, for which at least a 6 mm margin is recommended [3]. …”

“…In cutaneous SCC, tumor size larger than 2 cm, gender, preceding lesions, histological findings such as the degree of the differentiation, and location of tumors have been reported as prognostic factors of local recurrence, metastasis, and disease-specific death [1, 3, 5, 6]. The poor prognostic factors of SCC in this case were male, the poor differentiation, the tumor size, and rapid growth, which meant that this case had a high risk of metastasis and disease-specific death.…”