2006
DOI: 10.1097/01.sap.0000200734.74303.d5
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Squamous Cell Carcinoma Developing on Burn Scar

Abstract: Having high aggressive features, the suspicion of development of SCC in burn scar should be kept in mind, so patients with burn scar must be followed periodically.

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Cited by 37 publications
(10 citation statements)
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“…These tumors also develop on other wounds, including pressure sores ( 7 ), venous stasis ulcers ( 8 ), traumatic wounds ( 9 ), osteomyelitis ( 10 ), fistulas ( 11 ), leprosy ulcers ( 12 ) and lacerations ( 13 ). Burn scars are reported to have a rate of carcinomatous change of 2% ( 14 ). The most common type of Marjolin's ulcer is squamous cell carcinoma, followed by basal cell carcinoma, sarcoma and melanoma ( 15 , 16 ).…”
Section: Discussionmentioning
confidence: 99%
“…These tumors also develop on other wounds, including pressure sores ( 7 ), venous stasis ulcers ( 8 ), traumatic wounds ( 9 ), osteomyelitis ( 10 ), fistulas ( 11 ), leprosy ulcers ( 12 ) and lacerations ( 13 ). Burn scars are reported to have a rate of carcinomatous change of 2% ( 14 ). The most common type of Marjolin's ulcer is squamous cell carcinoma, followed by basal cell carcinoma, sarcoma and melanoma ( 15 , 16 ).…”
Section: Discussionmentioning
confidence: 99%
“…MU is a rare and aggressive cutaneous malignant transformation with an incidence of 0.1% to 2.5% after a long-term inflammatory or traumatic insult to the skin [16,17]. The main etiology tends to be post-burn scars and traumatic wounds [1].…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, there is a consensus on the importance of chronic irritation. Repeated ulceration to the scar and subsequent initiation of re-epithelialization provides a prolonged stimulus for cellular proliferation and may increase the rate of spontaneous mutations [17,19,20]. …”
Section: Discussionmentioning
confidence: 99%
“…Marjolin ulcer (MU) is an aggressive cutaneous malignancy that typically follows post-burn and/or post-traumatic lesions and scaring, as well as some chronic wounds (e.g., osteomyelitis, pressure sores, venous stasis ulcers, and dermatitis artefacta) [ 1 3 ]. The incidence of malignant transformation from burn scar tissue or other pathologic lesions is about 1% to 2% [ 4 , 5 ]. It takes 11 to 75 years from the initial injury to onset of malignant transformation, with an average of 30 to 36 years [ 1 , 6 ].…”
Section: Introductionmentioning
confidence: 99%