Squamous cell carcinoma in chronic hydradenitis suppurativa.A case report

Alexander, Saramma J.

doi:10.1002/1097-0142(197902)43:2<745::aid-cncr2820430251>3.0.co;2-d

Cited by 46 publications

(16 citation statements)

References 6 publications

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“…High [113.120-126] Low [113,[120][121][122][123][124][125][126] Various causative agents of Chronic Osteomyelitis Squamous cell carcinoma of the skin Basal cell carcinoma of the skin Fibrosarcoma Myeloma Angiosarcoma Rhabdomyosarcoma High [14 141-152] Low [153] Low [154,156,158,[160][161] Low [155] Low [157] Low [157] Various causative agents of Hidradenitis Suppurativa Lymphoma Squamous cell carcinoma of the skin Liver carcinoma Low [165] High [172,[174][175][176][177]180] Low [179] [30]. Finally, Chlamydia have been associated with lymphoproliferative disorders in adults [31,32]; in particular, ocular lymphomas have been linked to Chlamydia psittaci [33].…”

Section: Cholangiocarcinoma Cholangiocarcinomamentioning

confidence: 97%

“…Alexander reported a case of squamous cell carcinoma arising in HS of over 20 years duration. Interestingly, this carcinoma exhibited metastases in almost all organs [175]. Zachary et al described a squamous cell carcinoma that developed only three years after the appearance of severe HS of the perineum [176].…”

Section: Hidradenitis Suppurativa (Hs) and Cancer Developmentmentioning

confidence: 99%

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Chronic bacterial and parasitic infections and cancer: a review

Samaras

Rafailidis

Mourtzoukou

et al. 2010

J Infect Dev Ctries

112

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Background: A relatively underestimated facet of infectious diseases is the association of chronic bacterial and parasitic infections with cancer development. Therefore, we sought to evaluate the evidence regarding the association of such infections with the development of malignancy, excluding the overwhelming evidence of the association of Helicobacter pylori and cancer. Methodology: We searched Pubmed, Cochrane, and Scopus without time limits for relevant articles. Results: There is evidence that some bacterial and parasitic infections are associated with cancer development. The level of evidence of this association varies from high to low; in any case, a long time interval is mandatory for the development of cancer. A high level of evidence exists for the association of Salmonella Typhi with gallbladder and hepatobiliary carcinoma; Opisthorchis viverrini and Clonorchis sinensis with cholangiocarcinoma; Schistosoma hematobium with bladder cancer; chronic osteomyelitis with squamous cell carcinoma of the skin; and hidradenitis suppurativa with squamous cell carcinoma of the skin. In contrast, the level of evidence regarding the association of Chlamydia spp. with cancer is low. Mycobacterium tuberculosis is associated with lung cancer, albeit probably not etiopathogenetically. Conclusions: A considerable number of bacterial infections and parasitic infections are associated with the development of cancer. Further research into recognizing additional associations of bacterial and parasitic infections with cancer is mandatory.

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Section: Cholangiocarcinoma Cholangiocarcinomamentioning

confidence: 97%

Section: Hidradenitis Suppurativa (Hs) and Cancer Developmentmentioning

confidence: 99%

Chronic bacterial and parasitic infections and cancer: a review

Samaras

Rafailidis

Mourtzoukou

et al. 2010

J Infect Dev Ctries

112

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“…[1][2][3] Only wide surgical excision can cure the patient in the chronic, recurrent stage of the disease. It represents a deep-seated folliculitis, resulting in fibrosis, sinus formation and scarring.…”

mentioning

confidence: 99%

Perianal hidradenitis suppurativa: early surgical treatment gives good results in chronic or recurrent cases

Endo

Tamura

Ishikawa

1998

British Journal of Dermatology

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Hidradenitis suppurativa (HS) represents a chronic, recurrent, deep-seated folliculitis resulting in abscesses followed by the formation of sinus tracts and scarring. It is an uncommon disorder frequently involving the perianal region. We review the clinical and pathological features of 12 patients (10 men and two women) with perianal HS (PHS). The mean age at presentation was 43 years (range 24-65), and the mean duration of illness was 14 years (range 2-30). Two patients exhibited multiple areas of involvement, including the axilla and the nape of the neck, in addition to the perianal region. Histological examinations showed epidermis-lined sinuses surrounded by dense plasma cell infiltration in four of nine specimens. The complications related with PHS included anal fistula (seven patients), diabetes mellitus (four), malignant tumour (two) and sepsis (one). Three patients died of the complications. Eight patients underwent wide local excision. The defects were managed with a meshed split-thickness skin graft in five patients, and open treatment in the remainder. New lesions developed in untreated skin of two patients. However, no patient relapsed in the surgically treated sites. PHS is frequently complicated with anal fistula and is occasionally life-threatening as a result of the occurrence of malignant tumours or sepsis. Early surgical excision followed by meshed split-thickness skin graft can successfully cure the lesion without functional disturbance.

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“…The many known consequences of hidradenitis include psychological stress, lymphedema, fistulae, cancer, and even death [2,4,5,[7][8][9][10][11][12].…”

Section: Discussionmentioning

confidence: 99%