Squamous cell carcinoma of gall bladder: A rare case

Bai, Pasula Jijiya; Srujana, Shyamala; Quadri, S. S. S.; Kumari, N. Sreemani

doi:10.4103/0975-2870.118288

Cited by 1 publication

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“…Gall stones appear to play a major, probably due to chronic irritation, role as evidenced by the fact that approximately 90% of SCCs invariably have associated cholelithiasis [8] . It is mostly associated with cholesterol stones as shown by Cariati et al [9] The high incidence in countries like India could be explained by the association with parasitic infections [10] .…”

Section: Discussionmentioning

confidence: 99%

“…The other risk factors are adenoma, porcelain gall bladder, cholesytoenteric fistula, ulcerative colitis, anomalous biliopancreatic junction. Decreased expression of 23 nm and overexpression of c-erb B2 gene products have also been identified [8] .…”

Section: Discussionmentioning

confidence: 99%

“…Horgan et al reported non-significant benefits of adjuvant therapy but on separate analysis, chemoradiotherapy was found to be better than radiotherapy alone and the benefit was higher in node-positive and R1 resection [16] . The 5–year survival of SCC is around 1% owing to high proliferation index, low doubling time (81 vs 166 days of adenocarcinoma), and late diagnosis [8] , [17] . In our case, the patient presented with a liver abscess but unfortunately due to the metastatic nature of the disease only palliative treatment could be offered.…”

Section: Discussionmentioning

confidence: 99%

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Squamous cell carcinoma of the gallbladder masquerading liver abscess with review of literature

Jena

Meher

2022

International Journal of Surgery Case Reports

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Introduction and importance Squamous cell carcinoma of the gall bladder is a rare but aggressive tumor. It has a wide variety of presentations. Presentation as a liver abscess is a rare condition only 2 cases reported in the literature before. Case report A 45-year-old male patient presented to the emergency with complaints of fever, right upper quadrant pain, and jaundice. On evaluation, an initial diagnosis of the liver abscess was made. Due to the deteriorating condition of the patient, he was taken up for surgery. Upon exploration, there were multiple deposits over the bilateral lobes of the liver, so a controlled drainage of abscess cavity was done with biopsy from the wall of the gall bladder and liver metastasis was taken which showed squamous cell carcinoma of gall bladder with liver metastasis. The patient was given gemcitabine and oxaliplatin as palliative chemotherapy. He died after 11 months of presentation. Discussion and conclusion The aggressive and advanced nature of the disease at the presentation poses a formidable challenge in managing such patients but early diagnosis and surgical management can provide long term benefits.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%