Squamous cell carcinoma of the temporal bone: A current review

Lovin, Benjamin D.; Gidley, Paul W.

doi:10.1002/lio2.330

Cited by 51 publications

(64 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As with cholesteatoma, pain is not usually the presenting feature of these lesions. Neoplasms may also occur in the external auditory canal or even the temporal bone (typically SCC), but are exceedingly rare (incidence of approximately 1 per 1 000 000 population worldwide) (Lovin and Gidley, 2019). They can be difficult to identify, due to their symptomology overlapping with other benign conditions.…”

Section: Neoplasms Of the Earmentioning

confidence: 99%

The painful ear

Lai¹,

Oshinyemi

Grounds³

2020

InnovAiT: Education and inspiration for general practice

View full text Add to dashboard Cite

Otalgia, or ear pain, is a common presentation in general practice. It can be broadly divided into primary and secondary otalgia. Primary otalgia is pain that arises from pathology of the external, middle and inner ear. Secondary otalgia, or referred otalgia, is pain that arises from pathology outside the ear. There are many causes of secondary otalgia, due to the complex sensory innervation of the ear. History and physical examination are vital in determining the aetiology. This clinical review discusses the possible causes of ear pain, and provides a systematic approach to assessment and management, including when to refer to specialists.

show abstract

Section: Neoplasms Of the Earmentioning

confidence: 99%

The painful ear

Lai¹,

Oshinyemi

Grounds³

2020

InnovAiT: Education and inspiration for general practice

View full text Add to dashboard Cite

show abstract

“…Злокачественные опухоли наружного уха являются крайне редкой патологией, составляя 0,2 % всех злокачественных опухолей головы и шеи. В США ежегодно регистрируется около 300 случаев рака, локализованного в структурах уха [1,2], в России -до 200 случаев [3]. По официальным статистическим данным, в России заболеваемость злокачественными новообразованиями среднего уха, полости носа и придаточных пазух в 2018 г. составила 0,67 случая на 100 тыс.…”

Section: Introductionunclassified

Efficiecy of modern treatment methods for locally advanced cancer of the external ear: review

Мудунов

Хазарова

Алымов

2021

Opuholi golovy i šei

View full text Add to dashboard Cite

Skin cancer of external ear is a very aggressive type of cancer with spread to the parotid gland, bone structures of the lateral skull base, meninges and brain tissue. At the same time, malignant tumors of the external ear are very rare disease, accounting for 0.2 % of all malignant head and neck tumors. This fact explains the small amount of investigation in this scientific field. Now, does not exist unanimous opinion about the treatment tactics for patient with locally advanced ear cancer. Surgical tactics for volumes of block resections of the temporal bone are different. Controversial issues relate to the appropriateness of surgical treatment in general in the case of advanced tumor process. In this article we performed publication analysis devoted to selection of optimal treatment tactics for patient with locally advanced ear cancer.

show abstract

“…Злокачественные опухоли наружного уха являются крайне редкой патологией, составляя 0,2 % всех злокачественных опухолей головы и шеи. В США ежегодно регистрируется около 300 случаев рака, локализованного в структурах уха [1,2], в России -до 200 случаев [3]. Морфологическая структура злокачественных опухолей наружного уха многообразна.…”

Section: Introductionunclassified

Long-term results of treatment for patients with locally advanced external ear skin cancer

Мудунов

Хазарова

Болотин

2021

Opuholi golovy i šei

View full text Add to dashboard Cite

The study objective is to assess long-term results of treatment for patients with locally advanced external ear skin cancer.Materials and methods. This research work based on a retrospective and prospective analysis case history for patients with locally advanced external ear skin cancer. These are 45 patients, who received treatment in surgical department of head and neck tumors in Blokhin National Medical Research Center of Oncology between 1994 and 2020. Patient observation time averaged 30.0 ± 32.3 months (from 0.7 to 117.4 months, median 12.0 months). We divided patients into 3 groups depending on treatment methods. Group 1 consisted of patients who received combined or complex treatment (33.3 %, n = 15). Treatment for first group patients involved subtotal, lateral temporal bone resection or incomplete lateral resection and postoperative radiation therapy on the area of primary tumor and regional metastasis zone (total focal dose from 60 Gy). In the case of complex treatment, radiation therapy had carried out against background cisplatin introduction. The second group consisted of patients who received only surgical treatment (40.0 %, n = 18). Temporal bone resections were not performed for patients of the third group (26.7 %, n = 12). Treatment for patients of the third group involved one of the treatment methods: cryodestruction, laser destruction, photodynamic therapy, radiotherapy or chemoradiation treatment.Results. Five-year survival without signs of progression in a group of patients with locally advanced of the ear skin cancer, who received combined or complex treatment was 73.8 ± 13.1. Median progression-free survival not achieved. In the surgical treatment group 5 year progression-free survival was 40.4 ± 13.0, median was 34.1 months. In a group of patients who did not undergo temporal bone resection (3rd group) median progression-free survival was 4.5 months. Group differences are statistically significant (p <0.05). The most significant adverse prognosis factors that reduce overall survival for patients with locally advanced external ear skin cancer are positive histological margin (p = 0.0001, hazard ratio (HR) = 10.611, 95 % confidence interval (CI) 3.058-36.820), signs of destruction branch of the lower jaw/ zygomatic bone (p = 0.027, HR = 4.65, 95 % CI 1.193-18.116). Facial paralysis is the most unfavorable prognosis factor, reducing tumor-specific survival in patients with locally advanced outer ear skin cancer (p = 0.0001, HR = 19.146, 95 % CI 4.056-90.388).Conclusion. Combined/complex treatment of patients with locally advanced ear skin cancer (surgery with postoperative radiotherapy/chemoradiotherapy) provides better long-term results compared to other treatment options.

show abstract

Squamous cell carcinoma of the temporal bone: A current review

Cited by 51 publications

References 64 publications

The painful ear

The painful ear

Efficiecy of modern treatment methods for locally advanced cancer of the external ear: review

Long-term results of treatment for patients with locally advanced external ear skin cancer

Contact Info

Product

Resources

About