Squamous cell carcinoma of the cecum developing in a patient with long-standing ulcerative colitis and a coexistent carcinoid tumor in the appendix: A case report

Abstract

Squamous cell carcinoma (SCC) of the colon is a rare tumor that accounts for 0.1%-0.2% of colonic malignancies. However, pure SCC of the cecum is extremely rare. Although SCC of the colon is a rare complication of idiopathic inflammatory bowel disease (IBD), SCC of the cecum in the context of IBD has not been previously reported in the English literature. We report a case of the coexistence of SCC of the cecum and a carcinoid tumor in a 46-year-old female with long-standing pan-ulcerative colitis.

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“…Indeed, evidence for this process is provided by Balsano [13], who describes two cases of caecal SCC in patients who had undergone appendicectomy and right inguinal hernia repair complicated by post-operative chronic sinus and enterocutaneous fistula formation. The association between IBD and SCC occurring within the rectum is well reported [8,14], although there has only been a single case of caecal SCC arising in patient with longstanding ulcerative colitis (UC) [15]. Interestingly, this case also had a coexisting neuroendocrine tumour, which has also been described in a case report of rectal SCC [16].…”