“…2,3 Other aetiologies include ionising radiation, human papilloma virus infection, chemical agents, immunocompromised patients, genetic conditions, traumatised skin and non-healing skin also known as Marjolin's ulcer. [2][3][4][5][6] Squamous cell carcinoma is the most frequently encountered malignancy of the distal lower extremity, as opposed to basal cell carcinoma, melanoma or sarcomas. [2][3][4][5][6] The differential diagnosis for foot squamous cell carcinoma includes actinic keratosis, keratoacanthoma, squamous cell carcinoma in situ or Bowen's disease, basal cell carcinoma, eccrine poroma, verruca plantaris, reactive hyperplasia, pyogenic granulomas, psoriasis, repetitive trauma, bacterial or fungal infection, sweat gland carcinoma, amelanotic melanoma, sarcoma and Hodgkin's disease.…”