Square-wave voltammetric determination of bezafibrate in pharmaceutical formulations using a cathodically pretreated boron-doped diamond electrode

Ardila, Jorge Armando; Sartori, Elen Romão; Rocha‐Filho, Romeu C.; Fatibello‐Filho, Orlando

doi:10.1016/j.talanta.2012.10.033

Cited by 35 publications

(28 citation statements)

References 28 publications

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“…A linear relationship was observed between log I p against log v with a slope of 0.5282 (R 2 = 0.9982, n = 6), as shown in Figure 3. The slope of 0.5282 was close to the theoretical value of 0.5, which indicated that the reduction process of RB5 dye was mainly controlled by diffusion [30,31]. The effect of the RB5 dye concentrations was investigated and the results showed that the E p of RB5 dye at -258 mV showed no significant change in the peak position and the I p of the RB5 dye increased with the increasing concentration of RB5 dye.…”

Section: Results and Discussion Electrochemical Behaviour Of The Rb5 Dyesupporting

confidence: 71%

Voltammetric Determination of Reactive Black 5 (Rb5) in Waste Water Samples From the Batik Industry

Yaacob¹

2016

MJAS

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A cyclic voltammetry (CV) and differential pulse cathodic stripping voltammetry (DPCSV) studies of RB5 in Britton-Robinson buffer (BRB) at a hanging mercury dropping electrode (HMDE) are described. CV was carried out by cathodic and anodic potential scan over the range of +200 mV to -800 mV with no accumulation time and three well-defined pH-dependent cathodic peaks were observed. The effects of different scan rates, pH of BRB, repetitive cycle and increasing concentrations on the peak height and peak potential of the analyte were studied. The results showed that RB5 dye was adsorbed and irreversibly reduced at the mercury electrode, mainly under diffusion controlled in the optimum pH 4.0 of BRB. By using DPCSV, pH of BRB and various instrumental parameters such as scan rate, accumulation time, accumulation potential and pulse amplitude that may affect the peak height of RB5 were investigated and optimized for RB5 determination. Under the optimized parameters, the peak height was found to be linear with RB5 concentration in the range from 2.5 x 10 -7 mol L -1 to 2.0 x 10 -6 mol L -1 . A detection limit (3SD/m) of 1.3 x 10 -8 mol L -1 was achieved. The precision of the developed method in terms of RSD was 0.55% for intra-day measurement and 0.55%, 0.24% and 0.40%, for inter-day measurements, respectively. The developed method was successfully applied in the determination of RB5 in batik wastewaters with the mean recovery of 83.97 ± 4.78% to 97.93 ± 5.45% (0.5 x 10 -6 mol L -1 ), 95.91 ± 2.68% to 103.49 ± 1.32% (1.0 x 10 -6 mol L -1 ) and 99.17 ± 0.75% to 105.12 ± 0.28% (2.0 x 10 -6 mol L -1 ). The developed method is considered sensitive, precise, accurate, rugged, robust, fast and low cost for routine analysis of RB5 dye in batik wastewaters over the UV-VIS spectrometry method.Keywords: Reactive Black 5, differential pulse cathodic stripping, Britton-Robinson buffer, hanging mercury dropping electrode, batik wastewater samples Abstrak Kajian voltammetri berkitar (CV) dan voltammetri perlucutan denyut kebezaan (DPCSV) terhadap pewarna RB5 dalam larutan penimbal Britton-Robinson (BRB) menggunakan elektrod jatuhan raksa tergantung (HMDE) dihuraikan. CV dijalankan dengan mengimbas potential kathodik dan anodik dari +200 mV ke -800 mV tanpa masa pengumpulan dan tiga puncak diperhatikan selepas imbasan. Kesan perbezaan kadar imbasan, pH BRB, imbasan berkitar yang berulang dan peningkatan kepekatan RB5 ke atas ketinggian dan nilai keupayaan puncak dikaji. RB5 yang dijerap dan diturunkan secara tidak berbalik pada permukaan elektrod merkuri adalah dibawah kawalan difusi pada pH BRB yang optimum iaitu 4.0. Dengan menggunakan DPCSV, pH BRB dan parameter-parameter peralatan yang memberi kesan kepada ketinggian puncak seperti kadar imbasan, masa pengumpulan, keupayaan pengumpulan dan amplitud denyut telah dioptimumkan untuk analisis RB5. Ketinggian puncak berkadar terus dengan kepekatan RB5 dalam julat dari 2.5 x 10 -7 mol L -1 hingga 2.0 x 10 -6 mol L -1 . Had pengesanan adalah 1.3 x 10 -8 mol L -1 . Ketepatan (RSD...

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Section: Results and Discussion Electrochemical Behaviour Of The Rb5 Dyesupporting

confidence: 71%

Voltammetric Determination of Reactive Black 5 (Rb5) in Waste Water Samples From the Batik Industry

Yaacob¹

2016

MJAS

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“…whether they are predominantly hydrogen or oxygen terminated [21]; the predominance of a termination type can be attained by proper electrochemical pretreatments. This effect of surface termination was observed, for instance, in the determination of additives in food products [22][23][24] and of drugs in pharmaceutical formulations [25][26][27][28], when cathodically pretreated (predominantly hydrogen-terminated) BDD electrodes presented better performances.…”

Section: Introductionmentioning

confidence: 82%

“…Consequently, all subsequent experiments were carried out using a cathodically pretreated BDD. Previously, better results were also obtained in the analysis of several analytes when a predominantly hydrogen-terminated BDD electrode was used [22,24,25,28,35].…”

Section: Abz Determinationmentioning

confidence: 99%

Differential pulse voltammetric determination of albendazole in pharmaceutical tablets using a cathodically pretreated boron-doped diamond electrode

Lourenção

Baccarin

Medeiros

et al. 2013

Journal of Electroanalytical Chemistry

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“…As has been previously summarized [32], increased electroanalytical performances have been attained in the determination of additives in food products and drugs in pharmaceutical formulations after the BDD electrode was cathodically pretreated; more recently, this has happened e.g. for food colorants [33], and the pharmaceuticals albendazole [34], propylthiouracil [35], bezafibrate [36], hydroxychloroquine [37], hydroquinone [38], diclofenac [39], ciprofloxacin [40], and paracetamol/caffeine/orphenadrine [41] or propanolol/hydrochlorothiazide [42] simultaneously. However, in some cases, better results were attained with an anodically pretreated BDD electrode, e.g.…”

Section: Introductionmentioning

confidence: 99%

Amperometric flow-injection determination of the anthelmintic drugs ivermectin and levamisole using electrochemically pretreated boron-doped diamond electrodes

Lourenção

Medeiros

Thomasi

et al. 2016

Sensors and Actuators B: Chemical

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Square-wave voltammetric determination of bezafibrate in pharmaceutical formulations using a cathodically pretreated boron-doped diamond electrode

Cited by 35 publications

References 28 publications

Voltammetric Determination of Reactive Black 5 (Rb5) in Waste Water Samples From the Batik Industry

Voltammetric Determination of Reactive Black 5 (Rb5) in Waste Water Samples From the Batik Industry

Differential pulse voltammetric determination of albendazole in pharmaceutical tablets using a cathodically pretreated boron-doped diamond electrode

Amperometric flow-injection determination of the anthelmintic drugs ivermectin and levamisole using electrochemically pretreated boron-doped diamond electrodes

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