2010
DOI: 10.1002/dc.21593
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Squash cytomorphology of central neurocytoma: A study of five cases

Abstract: Intraoperative consultation is an important component in the surgical management of brain tumors. This study was undertaken to describe the cytomorphological features of central neurocytoma (CN) in squash smears. Squash smear of five CNs were reviewed. One to two millimeters of the biopsy material was crushed between two glass slides to make a thin film that was fixed in 95% alcohol and stained with haematoxylin and eosin (H&E). Cytological diagnoses were correlated with clinical and radiological data and fina… Show more

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Cited by 6 publications
(10 citation statements)
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“…Since their early description in 1982, CNs have been difficult to distinguish from oligodendrogliomas, ependymomas, subependymal giant cell astrocytomas and non-Hodgkin's lymphomas [1,3,6,7,8,9,10,11,12], mainly due to the fact that all of these tumors have a uniform cell population. This distinction is very important during intraoperative assessment because CNs require only tumor removal, while oligodendrogliomas require a wider surgical resection, ependymomas a less extensive excision and non-Hodgkin's lymphoma only diagnostic sampling [2,11].…”
Section: Discussionmentioning
confidence: 99%
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“…Since their early description in 1982, CNs have been difficult to distinguish from oligodendrogliomas, ependymomas, subependymal giant cell astrocytomas and non-Hodgkin's lymphomas [1,3,6,7,8,9,10,11,12], mainly due to the fact that all of these tumors have a uniform cell population. This distinction is very important during intraoperative assessment because CNs require only tumor removal, while oligodendrogliomas require a wider surgical resection, ependymomas a less extensive excision and non-Hodgkin's lymphoma only diagnostic sampling [2,11].…”
Section: Discussionmentioning
confidence: 99%
“…This distinction is very important during intraoperative assessment because CNs require only tumor removal, while oligodendrogliomas require a wider surgical resection, ependymomas a less extensive excision and non-Hodgkin's lymphoma only diagnostic sampling [2,11]. Very few cytology descriptions have been published in the literature concerning the cytodiagnosis of CNs during intraoperative assessment [6,7,8,9,10,11,12], and therefore, a thorough investigation of the cytologic features that have been described in previous reports was exhaustively examined. Only three cytologic features were common in all 18 cases previously reported for squash and imprint preparation during intraoperative assessment.…”
Section: Discussionmentioning
confidence: 99%
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