As vital infrastructure, the road network is essential for disaster mitigation and post disaster recovery. However, it is also vulnerable to natural disasters, impacting their ability to help increase city resilience. This study assesses the vulnerability of Padang City’s road network, especially in disaster-prone areas, to ensure continued functionality during emergencies, as the city is frequently exposed to natural hazards such as earthquakes, tsunamis, coastal erosion, and floods. This study delves into assessing the vulnerability of Padang’s road network, employing spatial analysis (GIS) to evaluate various factors, including disaster risk, road conditions, materials, types, and proximity to land uses. The study identifies three vulnerability zones: low, medium, and high, with a high concentration of highly vulnerable roads in coastal areas. It emphasizes the need for infrastructure resilience and a holistic approach including design, materials, maintenance, and disaster preparedness. Land use also plays a role, with commercial and residential zones facing higher vulnerability. The study recommends material upgrades, enhanced maintenance practices, increased road capacity, and integrating disaster risk into spatial planning. Overall, this research contributes to the knowledge base of road network vulnerability, offering valuable insights for disaster mitigation strategies to improve the sustainability of vulnerable regions like Padang City