A numerical study is made on the dynamic through-soil interaction between underground station and nearby pile supported surface structure on viscous-elastic soil layer, under vertically incident S wave. This paper focuses on the dynamic interaction and the interactive influence on seismic response of adjacent surface structure and underground structure. To this end, ANSYS has been further developed for calculation in frequency domain, in which hysteretic damping can be considered, so that structure-soil-structure interaction (SSSI) can be investigated via direct methodology. Discussion is made on the influence of arrangement of structures, distances between structures, shaking direction of seismic wave, shear wave velocity and damping of soil, scale and burial depth of underground structure, storey number, stiffness, style and pile length of surface structure on SSSI, in terms of horizontal acceleration of surface structure and horizontal relative displacement of underground structure. Maximum acceleration and displacement is also presented for 12 seismic inputs. Arrangement and shaking direction are two of the most important factors. The response can be either amplified or attenuated according to the distance, related to dynamic properties of the overall system. The underground structure, surrounded by building with the fundamental frequency approximate to that of free field, is heavily affected.